Table 7.
Association of inflammatory and metabolic indices with preeclampsia severity
| LR+ | LR- | Cut-off * | Sensitivity | Specificity | AUC | %95 CI | P-value | |
|---|---|---|---|---|---|---|---|---|
| Uric acid/Albumin ratio | 1.9 | 0.49 | > 0.1631 | 68.4% | 64% | 0.708 | 0.65–0.77 | < 0.001 |
| Fibrinogen/Uric acid ratio | 1.79 | 0.61 | < 93.84 | 59.3% | 66.9% | 0.669 | 0.60–0.73 | < 0.001 |
| Uric acid/Creatinine ratio | 1.30 | 0.77 | > 9.02 | 56.1% | 56.7% | 0.568 | 0.50–0.63 | 0.037 |
| Creatinine/Body weight ratio | 1.76 | 0.61 | > 0.0084 | 60% | 65.9% | 0.672 | 0.61–0.73 | < 0.001 |
| AST/PLT ratio | 1.48 | 0.68 | > 0.0837 | 59.4% | 59.8% | 0.623 | 0.56–0.68 | < 0.001 |
| AST/ALT ratio | - | - | - | - | - | - | - | 0.614 |
| FIB 4 | 1.23 | 0.81 | > 0.7189 | 54.8% | 55.5% | 0.569 | 0.51–0.63 | 0.033 |
| FIB 5 | 1.37 | 0.65 | < 42.75 | 66.7% | 51.4% | 0.591 | 0.52–0.66 | 0.010 |
* Cut-off values were found according to Youden index; LR+ Positive likelihood ratio; LR- Negative likelihood ratio; AUC Area under the curve; CI Confidence interval; AST Aspartate aminotransferase; ALT Alanine aminotransferase; PLT Platelet count; FIB 4 Fibrosis 4 index; FIB 5 Fibrosis 5 index