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. 2025 Sep 19;24:281. doi: 10.1186/s12944-025-02708-1

Table 2.

Baseline characteristics of the study participants stratified by BRI quartile

Categories Model 1 Model 2 Model 3 Model 4
β(95%CI) P-value β(95%CI) P-value β(95%CI) P-value β(95%CI) P-value
biological age BRI 2.16 (1.97, 2.34)  < 0.001 0.59 (0.54, 0.63)  < 0.001 0.58 (0.53, 0.62)  < 0.001 0.37 (0.33, 0.42)  < 0.001
BRI Quartile
Q1 0(Ref) 0(Ref) 0(Ref) 0(Ref)
Q2 8.30 (7.53, 9.07)  < 0.001 1.09 (0.87, 1.31)  < 0.001 1.10 (0.87, 1.32)  < 0.001 0.87 (0.64, 1.09)  < 0.001
Q3 12.24 (11.30, 13.18)  < 0.001 2.01 (1.78, 2.25)  < 0.001 1.97 (1.73, 2.20)  < 0.001 1.40 (1.17, 1.63)  < 0.001
Q4 14.21 (13.26, 15.16)  < 0.001 3.35 (3.10, 3.61)  < 0.001 3.31 (3.06, 3.55)  < 0.001 2.11 (1.86, 2.35)  < 0.001
P for trend  < 0.001  < 0.001  < 0.001  < 0.001
biological aging OR (95%CI) P-value OR (95%CI) P-value OR (95%CI) P-value OR (95%CI) P-value
BRI 1.20 (1.17, 1.22)  < 0.001 1.33 (1.30, 1.37)  < 0.001 1.33 (1.30, 1.37)  < 0.001 1.25 (1.22, 1.28)  < 0.001
BRI Quartile
Q1 1(Ref) 1(Ref) 1(Ref) 1(Ref)
Q2 1.32 (1.19, 1.46)  < 0.001 1.77 (1.57, 1.99)  < 0.001 1.80 (1.59, 2.04)  < 0.001 1.69 (1.33, 1.76)  < 0.001
Q3 1.73 (1.54, 1.94)  < 0.001 2.77(2.42, 3.16)  < 0.001 2.78 (2.42, 3.20)  < 0.001 2.34 (1.82, 2.43)  < 0.001
Q4 2.68 (2.38, 3.02)  < 0.001 5.07(4.41, 5.82)  < 0.001 5.11 (4.47, 5.85)  < 0.001 3.52 (2.74, 3.69)  < 0.001
P for trend  < 0.001  < 0.001  < 0.001  < 0.001

BRI Body Roundness Index, PIR Poverty income ratio, CVD Cardiovascular disease, DM Diabetes mellitus, DII Dietary Inflammatory Index, Asc Ascorbic Acid, OR Odds ratio, CI Confidence interval, β Coefficient

Model 1: not adjusted

Model 2: adjusted for age, sex, and race

Model 3: adjusted for model 2, additionally adjusted for marital status, PIR, educational level, smoking status, alcohol intake, and physical activity

Model 4: adjusted for model 3, additionally adjusted for CVD, Hypertension, DM, Dietary fiber, DII, Zinc intake, Asc intake