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. 2025 Jul 24;171(1):131–151. doi: 10.1002/ijgo.70258
Best practice advice
  • All women with cancer in pregnancy should be managed within a MDT with expertise in this area and should have a named obstetrician by the first trimester. Continuity of care within the MDT is recommended

  • First‐trimester dating scan before commencing treatment, and second‐trimester anomaly scan and serial growth scans during treatment are recommended. A cervical assessment is recommended if the patient is at high risk of preterm labor

  • All women on chemotherapy or other treatment should have vaccinations as per local policies

  • NIPT testing should be avoided in women with known cancer in pregnancy

  • Maternal risks of sepsis, thrombosis, preterm delivery, CS, and postpartum hemorrhage should be considered and discussed

  • Fetal risks of miscarriage, structural defects if conceived on treatment, prematurity and related complications, low birth weight, and stillbirth should be considered and discussed

  • Consider low‐dose aspirin if the patient is at high risk of pre‐eclampsia, in line with the FIGO initiative

Pragmatic practice advice
  • An antenatal care plan can be discussed with the regional unit or with advisory boards to deliver as much cohesive care as possible

  • Usual antenatal care should not be compromised in women with cancer in pregnancy

  • All women with cancer in pregnancy should be informed of their options for management from the first trimester, including the risk of preterm delivery and the option of termination of pregnancy