Table 1 –

Patient demographics

	UK Cohort (n=57)	US Cohort (n=13)	SA Cohort (n=10)	p-value
Gender	F=42, M=15	F=10, M=3	F=8, M=2	0.899
Age at diagnosis (years)	11.9 [8.5–13.3]	12.3 [9.9–17.7]	9.7 [8.8–12.8]	0.096
Duration of disease at 1st biomarker measurement (yrs)	2.2 [0.6–4.1]	0.8 [0.2–5.2]	2.1 [0.1–2.9]	0.727
Follow-up period (months)	12 [6–23]	20 [5–41]	8 [5–18]	0.447
Number of follow-up visits	3.0 [2.0–3.0]	2.0 [2.0–2.0]	2.5 [2.0–5.0]	0.212

Values include counts for gender and median values and interquartile ranges (in square brackets) for all other data. F= female, M = male. Yrs = years. Chi-squared or Kruskal-Wallis tests were used to compare demographic factors across the patient cohorts.