Table 3:
Hazard ratios for state transition in the full and simplified models.
Full model - both AGP and CP impact on all state transitions | ||
---|---|---|
State transitions | AGP | CP |
Inactive→active LN | 1.80 (1.08, 3.01) | 0.46 (0.17,1.28) |
Active→inactive LN | 1.22 (0.78, 1.91) | 0.33 (0.18, 0.62) |
Simplified model - AGP impacts on the inactive→active transition (predicting flare), and CP on the active→inactive transition (predicating remission) | ||
Inactive→active LN | 1.49 (1.10, 2.02) | - |
Active→inactive LN | - | 0.60 (0.39, 0.93) |
Hazard ratios (evaluated at mean factor values) and 95% confidence intervals shown. AGP = alpha-1-acid-glycoprotein, Ceruloplasmin = CP, LN = lupus nephritis.