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. Author manuscript; available in PMC: 2025 Sep 20.
Published in final edited form as: Clin Immunol. 2018 Nov 2;198:71–78. doi: 10.1016/j.clim.2018.10.021

Table 3:

Hazard ratios for state transition in the full and simplified models.

Full model - both AGP and CP impact on all state transitions
State transitions AGP CP
Inactive→active LN 1.80 (1.08, 3.01) 0.46 (0.17,1.28)
Active→inactive LN 1.22 (0.78, 1.91) 0.33 (0.18, 0.62)
Simplified model - AGP impacts on the inactive→active transition (predicting flare), and CP on the active→inactive transition (predicating remission)
Inactive→active LN 1.49 (1.10, 2.02) -
Active→inactive LN - 0.60 (0.39, 0.93)

Hazard ratios (evaluated at mean factor values) and 95% confidence intervals shown. AGP = alpha-1-acid-glycoprotein, Ceruloplasmin = CP, LN = lupus nephritis.