Table 1. MoLEP aim and objectives.

Aim Demonstrate the feasibility of M. leprae transmission interruption and long-term reduction of MDT needs, through comprehensive evidence-based interventions, which include SDR-PEP, and setting standards for replication.

Primary objectives: Implement an integrated approach to interrupt M. leprae transmission in the Morogoro region: a. Strengthen health system capacity for leprosy in the Morogoro region b. Enhance early detection and post-exposure prophylaxis of leprosy contacts using SDR-PEP and establish related documentation (reporting and monitoring)

Secondary objectives: a. Develop an M. leprae transmission interruption implementation model that can be scaled up nationally and replicated in other endemic countries b. Operationalize the SDR donation model

Explorative objectives: a. Consider potential to integrate innovative approaches such as digital tools to support diagnosis and to streamline and standardize data collection; including the data of contacts for SDR-PEP b. Integrate antimicrobial resistance monitoring and infection status surveillance using rapid diagnostic tests (RDTs) c. Explore possibility of integration of AI (Artificial Intelligence) based EPCON model into data of Digital Health Information System 2 (DHIS2) portal which would help identify probable high-risk clusters (hotspots) for focused early screening and case detection campaigns