. 2025 Sep 19;29(10):466. doi: 10.1007/s00784-025-06543-7

Table 4.

Tooth-related data from retrospective studies. Root Canal treatment (RCT), secondary root canal treatment (SRCT), periapical lesion (PAL)

Author/s	Endodontic procedure	Diagnosis	Used technique
Hsiao et al., 2009 [17]	26 RCTs, 8 SRCTs	34 PALs	Not reported.	Rotary instruments. Crown-down method.	NaOCl	Warm vertical or cold lateral condensation with gutta-percha or RealSeal.	Not reported.	Not reported.
Dereci et al., 2016 [19]	34 RCTs, 3 SRCTs	37 PALs	Not reported.	Reciprocating instruments. Use of apex locator.	2.5% NaOCl 5 ml 17% EDTA 2 ml 2% chlorhexidine Additional chemicals for dissolving gutta-percha cones.	Single cone obturation technique with gutta-percha cone and resin based sealer (AH Plus).	Direct restoration with composite.	Not reported.

Author/s

Endodontic procedure

Diagnosis

Used technique

Anesthesia

Instrumentation

Irrigation

Obturation

Restoration

Antibiotic regimen

Hsiao et al., 2009 [17]

26 RCTs,

8 SRCTs

34 PALs

Not reported.

Rotary instruments.

Crown-down method.

NaOCl

Warm vertical or cold lateral condensation with gutta-percha or RealSeal.

Not reported.

Dereci et al., 2016 [19]

34 RCTs,

3 SRCTs

37 PALs

Not reported.

Reciprocating instruments.

Use of apex locator.

2.5% NaOCl

5 ml 17% EDTA

2 ml 2% chlorhexidine

Additional chemicals for dissolving gutta-percha cones.

Single cone obturation technique with gutta-percha cone and resin based sealer (AH Plus).

Direct restoration with composite.

Not reported.