Table 2.

Sequence defined mutations

Clone	Sequences			Total bases	Deletions	Point mutation	Mutation rate*
	Mutated	Not mutated	Ratio
AID Transfected RHA2/12B3 Subclones (35 generations)
A06	21	12	1.75	11253	3	31	8.1
A21	17	13	1.31	10230	0	21	5.9
A46	15	12	1.25	9207	1	26	8.4
A63	19	21	0.90	13640	0	34	7.1
A88	38	29	1.30	22847	4	52	7.0
A93	46	32	1.44	26598	3	67	7.5
Total	156	119	1.31	93775	11	231	7.4†
RAMOS Subclones (34 generations)
R17	17	23	0.74	13640	0	23	5.0
R38	10	27	0.37	12617	0	10	2.3
R87	19	24	0.79	14663	0	28	5.6
Total	46	74	0.62	40920	0	61	4.3†

^*10⁻⁵ × bp/gen. 

^† Significance of t test P < 0.01.