Figure 1.

Percentage of participants taking metformin (in study or out of study) by year and treatment group. The upper panel includes only exams in participants without diabetes or with diabetes from the time period before the diabetes management change (i.e., before the first examination with diabetes and HbA_1c ≥7.0%). The lower panel includes all examinations in all participants, with or without diabetes. The x-axis labels denote the DPP follow-up years (DPP Y01, etc.) and DPPOS follow-up years (OS Y1, etc.). MET, metformin; PLAC, placebo.