Skip to main content
. 2025 Aug 26;48(10):1668–1675. doi: 10.2337/dci25-0032

Table 3.

Select DPP/DPPOS outcomes evaluated in this analysis

Outcome Brief definition Reference no. for detailed description
Diabetes Fasting glucose ≥126 mg/dL or 2-h glucose ≥200 mg/dL, confirmed 4
Cancer Cancer of any type except for non-melanoma skin cancer 9
Obesity-related cancer Cancer of the following types: meningioma, multiple myeloma, or cancer of the esophagus, kidneys, uterus, ovaries, thyroid, breast (postmenopausal), liver, gallbladder, upper stomach, pancreas, colon, or rectum 9
Nephropathy Urine albumin–to–creatinine ratio ≥30 mg/g or eGFR <45 mL/min/1.72 m2 confirmed at next visit or end-stage kidney disease 10
MACE Major adverse cardiovascular event: nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death 11
Mortality Death from any cause 12

eGFR, estimated glomerular filtration rate.