ALK	Anaplastic lymphoma kinase
BBB	Blood–brain barrier
BMs	Brain metastases
CNS	Central nervous system
DCR	Disease control rate
EGFR	Epidermal growth factor receptor
IC-ORR	Intracranial objective response rates
iDCR	Intracranial disease control rate
iORR	Intracranial objective response rate
iPFS	Intracranial progression-free survival
NSCLC	Non-small cell lung cancer
OS	Overall survival
PFS	Progression-free survival
SRS	Stereotactic radiosurgery
TKIs	Tyrosine kinase inhibitors