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Immunohistochemical analysis of bursa of Fabricius. MDV maternal Ab-negative chickens were inoculated with rMd5 (A), rMd5Δpp38 (B), or mock-inoculated (C). Bursa of Fabricius were harvested 6 days after inoculation and stained with glycoprotein B mAb. Antigen expression is severely impaired in rMd5Δpp38, showing that pp38 is involved in early cytolytic infection in lymphocytes. (Bar = 100 μm.)
