Table 3.
The Incidence of Delayed Excretion of MTX (44-Hour Concentration > 1 μmol/L)
| Time (h) |
Loading Dose (%) |
LR/eGFR (mL/min/1.73 m2) | I/HR/eGFR (mL/min/1.73 m2) | ||||
|---|---|---|---|---|---|---|---|
| 160 | 100 | 80 | 160 | 100 | 80 | ||
| 0.5 | 0 | 25.4% | 67.0% | 84.3% | 50.1% | 86.5% | 99.5% |
| 5 | 22.9% | 65.8% | 83.9% | 48.4% | 87.3% | 99.6% | |
| 10 | 21.7% | 64.3% | 83.1% | 46.7% | 86.4% | 99.4% | |
| 15 | 20.4% | 62.9% | 81.6% | 45.4% | 85.7% | 99.4% | |
| 20 | 21.5% | 62.1% | 79.9% | 44.2% | 84.6% | 99.5% | |
| 1 | 0 | 25.4% | 67.0% | 84.3% | 50.1% | 86.5% | 99.5% |
| 5 | 20.8% | 63.6% | 82.5% | 46.1% | 86.3% | 99.6% | |
| 10 | 19.6% | 62.5% | 81.0% | 45.0% | 85.3% | 99.5% | |
| 15 | 19.0% | 60.9% | 80.5% | 43.9% | 84.5% | 99.4% | |
| 20 | 20.3% | 59.9% | 79.0% | 43.3% | 83.4% | 99.4% | |
Abbreviations: LR, low-risk; I/HR, intermediate and high-risk; eGFR, estimated Glomerular Filtration Rate.