Figure 6.
Expression of SDF-1 and CXCR4 in the adult mouse DG. (A–C) Coronal sections through the hippocampus of CD-1 adult mice. CXCR4 is expressed in scattered cells in the dg hilus and lining the dg blades (arrows point to four such cells) (A). Double labeling with BrdUrd (brown) suggests that some of the CXCR4-expressing (blue) cells are still dividing (B). Arrowheads in B indicate double-labeled cells; singly BrdUrd-labeled or CXCR4-expressing cells appear in the same field. SDF-1 is expressed in the blades of the dg, and scattered SDF-1-expressing cells (arrows) also appear in the hilus of the dg (C).