Table 2.
Hormonal and radiological changes over time.
| Variables | T0 (n = 62) | T6 (n =40) | T12 (n = 46) | T24 (n = 42) | TLAST (n = 62) | P-value (paired data) |
|---|---|---|---|---|---|---|
| PRL (ng/mL) | 187.4 (85.0 - 742.6) |
10.5 (4.2 - 22.8)* |
7.3 (3.2 - 24.7)* |
5.8 (1.3 - 20.2)* |
10.8 (2.8 - 19.8)* |
<0.0001 |
| Maximum diameter (mm) |
9.5 (5.0 - 18.8) |
10.5 (4.3 - 15.0)* |
7.0 (4.0 - 12.0)* |
5.0 (3.3 - 11.0)*1 |
4.5 (0.0 - 10.8)*1 |
<0.0001 |
| Volume (mm3) | 1361 (133 - 2913) |
842 (541 - 1217)* |
157 (46 - 735)*1 |
137 (28 - 503)*1 |
84.0 (20 - 707)* |
<0.0001 |
| Δ diameter (%) | – | 25.0 (0.0 - 44.3) |
22.5 (0.0 - 40.0) |
37.2 (0.0 - 58.9)*1 |
54.2 (20.4 - 100.0)1 |
<0.0001 |
| Δ volume (%) | – | 70.0 (61.3 - 82.1) |
68.2 (38.9 - 85.8)1 |
78.7 (62.8 - 90.8)*1 |
82.1 (63.1 – 96.6)*1 |
0.002 |
*difference vs T0; 1difference vs last control.
The comparison between two time points was assessed by paired T-test for normally distributed variables and Wilcoxon test for not normally distributed variables. The comparison among all the time points was performed by paired data ANOVA for normally distributed variables or Friedmann test for not normally distributed variables.Significant differences are shown in bold characters.