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The sebocyte HPA-like axis may contribute to sebocyte differentiation (decreased proliferation and enhanced lipogenesis) and anti-inflammatory signaling (reduced IL-8 secretion). Data from refs. 8, 21, 34–36; this manuscript; and ††. ACTH, adrenocorticotropin; BP, binding protein; EGF, epidermal growth factor; MC-R, melanocortin receptor; R, receptor
