Table 2.

Validation metrics.

Metric	ACC/AHA ASCVD function (optimal threshold, 6.50%)	2008 FHS global CVD function (Optimal threshold, 5.92%)
Sensitivity	56.5% (95% CI, 46.4%-67.1%)	69.6% (95% CI, 56.4%-80.8%)
Specificity	49.4% (95% CI, 39.4%-59.0%)	39.3% (95% CI, 29.6%-50.0%)
PPV	36.6% (95% CI, 27.8%-45.3%)	37.2% (95% CI, 26.7%,47.7%)
NPV	64.9% (95% CI, 55.2%-73.8%)	67.9% (95% CI, 58.1%-77.4%)

ACC/AHA, American College of Cardiology/American Heart Association; ASCVD, atherosclerotic cardiovascular disease; FHS, Framingham Heart Study; CI, confidence interval; CVD, cardiovascular disease risk calculator; NPV, negative predictive value; PPV, positive predictive value.