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. 2025 Aug 13;9(6):103005. doi: 10.1016/j.rpth.2025.103005

Table 3.

Baseline characteristics of TTP patients in sensitivity analysis.

Characteristic Total cohort (N = 85) Cohort with MACE (n = 30) Cohort without MACE (n = 55) P value
Age, y, median (IQR) 54.0 (44.0,64.0) 56.0 (45.0, 64.8) 54.0 (44.0, 63.0) .90
Sex, % .51
 Male 30.6% 36.7% 27.3%
 Female 69.4% 63.3% 72.7%
Race, % .44
 Black 62.4% 56.7% 65.4%
 White 34.1% 36.7% 32.8%
 Other 3.5% 6.6% 1.8%
Ethnicity, % .29
 Not Hispanic or Latino 76.5% 70.0% 80.%
 Hispanic or Latino 1.2% 3.3% 0%
 Other/unknown 22.3% 26.7% 20%
Total cholesterol, mg/dL, median (IQR) 173.0 (145.0, 210.8) 169.0 (150.0, 205.0) 177.0 (142.5, 211.5) .71
HDL cholesterol, mg/dL, median (IQR) 46.0 (41.0, 62.0) 46.0 (41.0, 59.8) 47.0 (40.5,65.0) .25
LDL cholesterol, mg/dL, median (IQR) 94.0 (79.8, 124.0) 94.0 (81.0, 106.8) 96.0 (76.5, 131.3) .51
Systolic blood pressure, median (IQR) 131.0 (120.0, 146.8) 144.0 (122.0, 162.0) 128.0 (120.0, 140.0) .05
Diastolic blood pressure, median (IQR) 73.5 (67.0, 82.0) 71.0 (64.0, 85.0) 74.0 (68.0, 81.0) .62
Antihypertensive medication, % 67.1% 70% 65.5% .85
Smoker, % 50.6% 50.0% 50.9% .91
Diabetes mellitus, % 32.9% 36.7% 30.9% .76
Lupus or any autoimmune disease, % 22.4% 13.3% 27.3% .22
History of DVT, % 17.6% 23.3% 14.5% .41
History of CKD, % 38.8% 40.0% 38.2% .77

CKD, chronic kidney disease; DVT, deep vein thrombosis; HDL, high-density lipoprotein; IQR, interquartile range; LDL, low-density lipoprotein; MACE, major adverse cardiovascular event; TTP, thrombotic thrombocytopenic purpura.