Table 3.
Hepatitis B virus infection and chronic carriage in 1998 in relation to peak antibody concentration. Figures are numbers of breakthrough infections out of total number of children with antibody response
| Group and time of vaccination |
Peak antibody concentration (mIU/ml)
|
||||
|---|---|---|---|---|---|
| <10 | 10-99 | 100-999 | >999 | Total | |
| Group 1 (Nov 84-May 85) | 9*/10 (90) | 5/9 (56) | 4/26 (15) | 3/6 (50) | 21/51 (41) |
| Group 2 (Nov 84-May 85) | 3†/5 (60) | 1/3 (33) | 11/32 (34) | 3*/16 (19) | 18/56 (32) |
| Group 3 (Nov 84-May 85) | 0/0 | 2/2 (100) | 4/22 (18) | 8/39 (21) | 14/63 (22) |
| Group 4 (Oct 85-Sep 89) | 2*/5 (40) | 1/8 (13) | 10*/37 (27) | 11/141 (8) | 24/191 (13) |
| Group 5 (Oct 89-Sep 93) | 0/1 | 0/9 | 4/34 (12) | 5/146 (3) | 9/190 (5) |
| Group 6 (Oct 93-Jul 98) | 5†/18 (28) | 3/27 (11) | 3/73 (4) | 3/101 (3) | 14/219 (6) |
| Overall | 19/39 (49) | 12/58 (21) | 36/224 (16) | 33/449 (7) | 100/770 (13) |
*
One breakthrough infection resulted in chronic carriage.
†
Three breakthrough infections resulted in chronic carriage.