Skip to main content
. 2025 Aug 14;99(9):e00478-25. doi: 10.1128/jvi.00478-25

Fig 3.

Heatmap and time-series plots depict gene expression changes across infected and vaccinated pigs. Group A does not show significant responses throughout test, Groups B and C exhibit stronger responses with distinct temporal cluster profiles.

Temporal dynamics of the spectrum of IgG antibodies against ASFV antigens in infected pigs. (a) A timeline overview of the IgG responses to the 46 ASFV proteins in the three groups. Each rectangle indicates the average IgG signal against a specific ASFV protein (row) at a time point (column). (b) Distinct modes of the temporal dynamics of IgG responses in group B (upper panel) and group C (lower panel). Purple background, structural proteins; gray background, non-structural proteins. (c) Distinct modes of temporal dynamics of the IgG responses to 30 structural proteins, which are categorized into five clusters in groups B and C. In panels b and c, each light green line represents the IgG signal change against a specific protein, while the pink line reflects the dynamic mode based on the averaged IgG signals of all proteins in the corresponding cluster.