Infectious virus in VZV-infected skin implants. Implants were inoculated with P-Oka, V-Oka, or gC−-Oka and harvested 14, 21, or 28 days postinfection. Cell-associated virus was measured in an infectious focus assay, and PFU per implant was calculated. Error bars indicate the standard error of the mean. On day 21, all differences between strains were statistically significant (P ≤ 0.02, Student’s t test).