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Replication of HSV-1 KOS and the HSV-1 gC deletion mutant in thy/liv and skin implants
| Implant tissue | Mean log PFU/implant ± SE (no. of implants that yielded virus/no. analyzed)a
|
||
|---|---|---|---|
| KOS | ΔgC2-3rev | ΔgC2-3 | |
| Thy/liv | 6.6 ± 1.2 (2/2) | 5.4 ± 1.2 (2/2) | 6.5 ± 0.4 (3/3) |
| Skin | 6.7 ± 0.3 (6/8) | 7.6 ± 0.8 (8/8) | 6.1 ± 0.5 (3/10) |
Implants were inoculated with HSV-1 strains and harvested on day 4 (thy/liv) or day 6 (skin) after infection, and titers in cell lysates were determined.
