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. 2025 Sep 23;13:RP102756. doi: 10.7554/eLife.102756

Table 2. Contribution of empathic concern (EC), instrumental harm (IH), and impartial beneficence (IB) scores on participants’ behavior in study 2.

Tables 2a (placebo session) and 2b (oxytocin session) show the results of three multiple regression analyses. The dependent variables in the three analyses were hyperaltruism (κother – κself), relative harm sensitivity (otherβΔs – selfβΔs), and relative monetary sensitivity (otherβΔm – selfβΔm). Results in bold are further illustrated in Figure 5C and D.

a. Placebo condition
Predictors Hyperaltruism Relative harm sensitivity Relative monetary sensitivity
β SE t P β SE t P β SE t P
Intercept –0.085 0.123 –0.688 0.493 0.065 0.17 0.382 0.704 –0.205 0.266 –0.771 0.443
EC 0.005 0.004 1.162 0.248 0.006 0.006 1.086 0.281 –0.004 0.009 –0.444 0.658
IH –0.032 0.017 –1.904 0.06 –0.071 0.024 –3.005 0.003 0.035 0.037 0.967 0.336
IB 0.047 0.021 2.2 0.031 0.029 0.029 1 0.32 0.086 0.046 1.887 0.063
Context (gain vs. loss) –0.034 0.174 –0.197 0.844 –0.34 0.241 –1.412 0.162 0.323 0.375 0.862 0.391
EC × context 0.002 0.006 0.332 0.74 0.005 0.008 0.601 0.549 0.003 0.012 0.264 0.792
IH × context 0.018 0.024 0.737 0.463 0.077 0.033 2.297 0.024 –0.062 0.052 –1.187 0.238
IB × context –0.051 0.03 –1.711 0.091 –0.047 0.042 –1.14 0.257 –0.084 0.065 –1.295 0.199
b. Oxytocin condition
Intercept 0.138 0.125 1.1 0.275 0.056 0.109 0.511 0.611 0.049 0.253 0.195 0.846
EC 0.01 0.004 2.397 0.019 0.006 0.004 1.675 0.098 0.001 0.009 0.157 0.876
IH –0.047 0.017 –2.721 0.008 –0.037 0.015 –2.458 0.016 0.053 0.035 1.541 0.126
IB –0.034 0.019 –1.813 0.073 –0.009 0.016 –0.582 0.562 –0.041 0.038 –1.091 0.279
Context (gain vs. loss) –0.071 0.177 –0.401 0.69 0.092 0.154 0.596 0.553 –0.372 0.358 –1.04 0.301
EC × context 0.002 0.006 0.385 0.701 –0.002 0.005 –0.336 0.737 0.012 0.012 0.985 0.327
IH × context 0.008 0.024 0.323 0.747 0.006 0.021 0.272 0.786 –0.045 0.049 –0.918 0.361
IB × context –0.01 0.026 –0.384 0.702 –0.012 0.023 –0.526 0.6 0.024 0.053 0.457 0.649