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. 1998 Feb;72(2):1005–1012. doi: 10.1128/jvi.72.2.1005-1012.1998

TABLE 1.

Transcription mapping of KSHV in BC-1 cells with and without TPA

Probe no. ORFs encoded on probe Position (bp) Probe size (kb) mRNAs (kb) identified in BC-1a
Transcription class
Without TPA induction With TPA induction
1 K1,4 (v-CBP), 6 TR (366 bp) 6.715 6.0+ 6.0 II
1–6349 4.0 III
3.0 III
1.8 III
1.0 III
2 7, 8, 9, 10, 11 6900–16600 9.7 7.0 III
6.0 III
2.5 III
1.0 III
3 11, K2 (v-IL-6), 2 (DHFR), K3 (IEI) 16200–19700 3.5 8.0 III
6.0 III
3.1 III
2.0 III
1.0 ++ (K2[v-IL-6]) 1.0 II
4 K3 (IE1), 70 (TS), 19130–23906 4.776 4.0 III
K4 (v-MIP-II), K4.1 2.5 III
2.3+ 2.3 II
2.0 III
1.5 III
0.8 ++ (K4 [vMIP-II]) 0.8 II
5 K5 (IE1), K6 (v-MIP-I), 24839–28888 4.049 4.0 + 4.0 II
 K7 (nut-1) 1.3 + 1.3 II
1.1 +++ (T1.1/nut1) 1.1 II
6 K7 (nut-1) 28889–29676 0.787 9.0 III
1.1 ++++ (T1.1/nut-1) 1.1 II
7 16 (v-Bc12), 17 29677–30840 1.163 9.0 III
7.0 III
3.5 III
2.0 III
1.0 III
8 17 30841–32361 1.52 7.0 III
6.0 III
3.5 III
2.0 III
1.0 III
9 17, 18, 19 32362–34401 2.039 7.0 III
6.0 III
1.0 III
10 19, 20, 21 34021–36882 2.861 7.0 III
6.0 III
11 21, 22, 23, 24, 25 36883–43171 6.288 7.0 III
6.0 III
3.0 III
12 25, 26 43172–47193 4.021 7.0 III
2.0 III
13 26, 27, 28, 29b, 30 47517–50637 3.12 7.0 III
2.0 III
14 30, 31, 32, 33, 29a, 34, 35 50638–55722 5.084 8.0 III
6.0 III
3.0 III
15 34, 35 55269–55819 0.55 4.5 III
3.0 III
1.1 III
16 36, 37, 38, 39, 40, 41, 42 55820–62901 7.081 4.5 III
3.0 III
2.5 + 2.5 II
1.4 III
0.5 III
17 42, 43 62902–63403 0.501 9.0 III
6.0 III
4.5 III
3.0 III
2.5 III
1.4 III
18 43 63404–63793 0.389 9.0 III
4.5 III
3.0 III
19 43, 44 64037–66502 2.465 6.0 + 6.0 II
4.5 III
3.0 III
2.7 III
20 44, 45 66503–68324 1.821 9.0 III
4.0 III
2.5+ 2.5 II
1.5 +++ 1.5 II
21 45, 46, 47, 48, 49 68325–72191 3.866 8.0 III
2.5 III
1.5 III
0.8 III
22 49, 50, K8, K8.1, 52 72192–77087 4.895 7.0 III
4.0 III
1.8 + 1.8 II
1.5 + 1.5 II
23 52, 53, 54, 55, 56 77088–81046 3.958 3.0 III
2.0 III
1.3 III
24 56, 57 81047–83278 2.231 2.0 + 2.0 II
25 57, K9 (v-IRF1), K10 83279–86279 3.0 2.0 III
1.5 ++ (v-IRF) 1.5 II
26 K10 86879–90158 3.279 3.0 III
2.0 + 2.0 III
1.5 III
27 K10.1, K11 90159–92110 1.951 2.0 + 2.0 II
28 K11 92111–92468 0.357 4.5 III
3.0 III
2.0 + 2.0 II
29 K11, 58, 59 60, 61 92665–99864 7.199 6.0 III
3.0 III
2.0 + 2.0 II
30 61, 62, 63 99865–101232 1.367 2.0 III
1.7 III
31 62, 63, 64 100784–104075 3.291 2.0 III
1.7 III
32 64 104076–107008 2.932 5.0 III
3.0 III
2.0 III
1.7 III
1.2 III
33 64, 65, 66, 67, 67.5, 68 107940–115051 7.111 7.0 III
5.0 III
4.0 III
2.5 III
1.2 III
34 68 115052–115707 0.655 9.0 III
7.0 III
6.0 III
4.0 III
35 68, 69, K12 (kaposin) 115708–120725 5.017 4.0 III
0.7 ++++ (T0.7/kaposin) 0.7 II
36 K13 (v-FLIP) 120601–122590 1.989 6.0 + (v-FLIP, v-Cyc, LANA) 6.0 I
2.0 + (v-FLIP, v-Cyc) 2.0 I
37 K13 (v-FLIP), 122591–127392 4.801 6.0 ++ (v-FLIP, v-Cyc, LANA) 6.0 I
72 (v-Cyc), 73 (LANA) 2.0 ++ (v-FLIP, v-Cyc) 2.0 I
38 72 (v-Cyc) 122792–123565 0.773 6.0 ++ (v-FLIP, v-Cyc, LANA) 6.0 I
2.0 ++ (v-FLIP, v-Cyc) 2.0 I
39 K14, 74 (V-GCR), 75 127393–133381 5.988 6.0 + (v-FLIP, v,Cyc, LANA) 6.0 I
4.5 +++ 4.5 I
3.0 III
2.5 III
2.0 + (v-FLIP, v-Cyc) 2.0 I
40 K14 (v-Adh) 127882–128928 1.046 4.5 + 4.5 I
2.5 III
1.5 III
1.2 III
41 74 (v-GCR) 129513–129985 0.472 9.0 III
2.5 III
42 K15 135976–136278 0.302 9.0 III
6.0 III
a

Specific genes identified with specific sequence probes are indicated in paretheses. Relative transcription in BC-1 without TPA: −, none; +, low; ++, moderate; +++, high; ++++, very high. For abbreviations, see the legend to Fig. 1