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. 2025 Sep 10;16:1622819. doi: 10.3389/fneur.2025.1622819

Table 4.

The subgroup analysis for clinical outcome of aSAH patients.

Variables n (%) TyG-i > 8.804 TyG-i ≤ 8.804 OR (95%CI) p p for interaction
All patients 467 (100.00) 165/233 199/234 2.34 (1.48–3.70) <0.001
Gender 0.113
Female 277 (59.31) 96/140 120/137 3.24 (1.74–6.02) <0.001
Male 190 (40.69) 69/93 79/97 1.53 (0.76–3.05) 0.230
Age older than 65 years 0.618
No 360 (77.09) 139/181 158/179 2.27 (1.28–4.03) 0.005
Yes 107 (22.91) 26/52 41/55 2.93 (1.30–6.61) 0.010
Graeb score 0.406
0–4 433 (92.72) 156/210 191/223 2.07 (1.27–3.36) 0.003
5–12 34 (7.28) 9/23 8/11 4.15 (0.86–19.92) 0.076
SEBES score 0.896
0–2 249 (53.32) 88/127 103/122 2.40 (1.30–4.46) 0.005
3–4 218 (46.68) 77/106 96/112 2.26 (1.14–4.46) 0.019
mFS Score 0.421
0–2 169 (36.19) 62/76 82/93 1.68 (0.72–3.96) 0.233
3–4 298 (63.81) 103/157 117/141 2.56 (1.48–4.43) <0.001
WFNS score 0.225
1–3 361 (77.30) 141/174 174/187 3.13 (1.59–6.18) <0.001
4–5 106 (22.70) 24/59 25/47 1.66 (0.76–3.59) 0.200
Hunt Hess score 0.156
1–3 420 (89.94) 158/207 193/213 2.99 (1.71–5.24) <0.001
4–5 47 (10.06) 7/26 6/21 1.09 (0.30–3.92) 0.900
IVH 0.860
No 187 (40.04) 70/84 94/103 2.09 (0.86–5.10) 0.106
Yes 280 (59.96) 95/149 105/131 2.30 (1.33–3.95) 0.003
Loss of consciousness 0.187
No 322 (68.95) 123/153 157/169 3.19 (1.57–6.49) 0.001
Yes 145 (31.05) 42/80 42/65 1.65 (0.84–3.23) 0.143
Treatment modality 0.714
Endovascular intervention 213 (45.61) 85/110 93/103 2.74 (1.24–6.03) 0.013
Surgical clipping 254 (54.39) 80/123 106/131 2.28 (1.29–4.04) 0.005
Current smoking 0.270
No 387 (82.87) 133/186 169/201 2.10 (1.28–3.45) 0.003
Yes 80 (17.13) 32/47 30/33 4.69 (1.23–17.82) 0.023
Current drinking 0.786
No 416 (89.08) 147/204 181/212 2.26 (1.39–3.69) 0.001
Yes 51 (10.92) 18/29 18/22 2.75 (0.74–10.27) 0.132
Diabetes 0.376
No 441 (94.43) 154/216 193/225 2.43 (1.51–3.91) <0.001
Yes 26 (5.57) 11/17 6/9 1.09 (0.20–6.01) 0.920
Hypertension 0.472
No 222 (47.54) 74/92 114/130 1.73 (0.83–3.61) 0.142
Yes 245 (52.46) 91/141 85/104 2.46 (1.34–4.50) 0.004
History of heart disease 0.886
No 401 (85.87) 146/194 181/207 2.29 (1.35–3.87) 0.002
Yes 66 (14.13) 19/39 18/27 2.11 (0.76–5.82) 0.151
History of anticoagulant 0.694
No 454 (97.22) 161/226 195/228 2.39 (1.49–3.81) <0.001
Yes 13 (2.78) 4/7 4/6 1.50 (0.16–14.42) 0.725

OR, Odds Ratio, CI, Confidence Interval, mFS, modified Fisher scale; SEBES, Subarachnoid Hemorrhage Early Brain Edema Score; IVH, intraventricular hemorrhage; GCS, Glasgow coma score; WFNS, World Federation of Neurological Societies. Bold values: p < 0.05.