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. 2025 Sep 19;104(38):e44540. doi: 10.1097/MD.0000000000044540

Table 3.

Univariate and multivariate analysis of risk factors for loss of radioiodine avidity in DTC patients.

Characteristics Univariate analysis Multivariate analysis
OR 95% CI P-value OR 95% CI P-value
Age ≥ 55 1.4 0.5–3.5 >.05 1.1 0.4–2.7 >.05
Male 0.9 0.4–2.2 >.05 1 0.4–2.4 >.05
Tumor size T4 0.6 0.2–1.9 >.05 0.4 0.1–1.2 >.05
Lymph node metastasis N1 0.9 0.4–2.4 >.05 1.1 0.4–3.0 >.05
C-PTC 0.4 0.1–1.5 >.05 0.4 0.1–1.4 >.05
BRAF V600E and TERT mutations 2.8 1.1–7.5 <.05 4.1 1.3–12.8 .013

Bold values indicate statistical significance.

C-PTC = conventional papillary thyroid carcinoma, TERT = telomerase reverse transcriptase.