TABLE 2.
Biochemical activities of HSV-1 5/8/52, IT 5/8/52, and HSV-1 5/52 in the absence or presence of UL8
| Complex | Biochemical activity
|
|||
|---|---|---|---|---|
| ATPasea | Helicaseb | Primaseb | Leading strandb | |
| HSV-1 5/8/52 | 1.35 | 100 | 100 | 100 |
| IT 5/8/52 | ||||
| −UL8 | 1.40 | 26 | 7 | 195 |
| +UL8 | NDc | 31 | 6.6 | ND |
| HSV-1 5/52 | ||||
| −UL8 | 1.45 | 4.8 | 9 | 0 |
| +UL8 | ND | 32.6 | 53.2 | ND |
Expressed as nanomoles of Pi released per picomole of enzyme per hour.
Expressed as percentage of HSV-1 5/8/52 activity.
ND, not done.