TABLE 1.
Selection of WIN 52035-dependent mutants of HRV16
| Isolate no. | Relative plaquing efficiencya
|
||
|---|---|---|---|
| 1st plaquing | 2nd plaquing | 3rd plaquing | |
| 1 | 23 | 220 | 1,300 |
| 2 | 6 | 70 | 3,200 |
| 3 | 29 | 1,800 | 5,000 |
| 4 | 44 | 8,000 | 10,000 |
| 5 | 280 | 290 | 850 |
| 6 | 70 | 2,500 | 6,000 |
| 7 | 210 | 11,000 | 5,000 |
| 8 | 110 | 3,200 | 10,000 |
| 9 | 17 | 110 | 6,000 |
Defined as the plaque titer in the presence of 2 μg of WIN 52035 per ml divided by that in the absence of the drug.