Skip to main content
PLOS Global Public Health logoLink to PLOS Global Public Health
. 2025 Sep 24;5(9):e0005151. doi: 10.1371/journal.pgph.0005151

Perceived neighborhood safety, crime exposure, and chronic diseases among older Indians: The role of functional disabilities

Manacy Pai 1, T Muhammad 2, Adedayo Adeagbo 3, Waad Ali 4,*
Editor: Julia Robinson5
PMCID: PMC12459815  PMID: 40991579

Abstract

We examined the associations between perceived neighborhood safety, crime exposure, and the prevalence of chronic conditions and multimorbidity among older adults in India. Moreover, we examined whether these associations varied by functional disabilities measured by difficulties in activities of daily living (ADLs) and instrumental activities of daily living (IADLs). Data came from the World Health Organization’s Study on Global AGEing and Adult Health (SAGE), India Wave 2, conducted in 2015. Neighborhood safety was measured by perceptions of safety at home and while walking after dark, whereas crime exposure was assessed through reports of household victimization by violent crime in the past year. Chronic conditions were self-reported physician diagnoses of hypertension, diabetes, stroke, arthritis, angina, asthma, and lung disease, with multimorbidity defined as the presence of more than two chronic diseases. Multivariable regression analyses were used to examine the main associations and interaction terms to test the moderating role of ADL/IADL disabilities. The mean score of neighborhood safety (on a scale of 0–10) was 7.72 (SD: 2.05). Approximately 6% of the participants reported that they or someone in their household had been victims of violent crime in the previous year. Older adults with perceived neighborhood safety reported a lower number of chronic conditions (adjusted beta: -0.03, confidence interval [CI]: -0.04 to 0.01) and lower odds of multimorbidity (adjusted OR: 0.95, CI: 0.91 – 0.99). Those with crime exposure reported a higher number of chronic conditions (adjusted beta: 0.10, CI: 0.02 – 0.19). These associations were significantly more pronounced among those with ADL/IADL disabilities. Perceived neighborhood safety and crime exposure were significantly linked to chronic diseases and multimorbidity among older adults in India, particularly among those with functional disabilities. These findings underscore the need for targeted strategies to improve neighborhood safety and support among older Indians with functional disabilities.

Background

A longer life expectancy means that people live longer than before. However, the gap between life expectancy and healthy life expectancy, particularly in low- and middle-income countries (LMICs), is alarming [1]. While older adults in LMICs live longer, they endure a rising burden of chronic conditions and multimorbidity [24], with nearly 80% of premature mortality from chronic diseases occurring in these countries [5,6]. To facilitate healthy aging, it is important to address various factors that contribute to the prevalence of chronic conditions among older adults. Among these, neighborhood conditions stand out as a significant determinant of health and well-being [79]. The environment in which older adults live shapes their physical, mental, and social health [812], and plays a pivotal role in shaping their overall quality of life [13]. Considering that, with increasing age, people spend more time in their immediate neighborhoods and become increasingly dependent on community relationships, resources, and services [1416], unfavorable neighborhood conditions can be particularly detrimental to health in later life [17].

Research has shown that living in unsafe neighborhoods is associated with functional decline in older adults [18,19], as fear limits engagement in physical activity [2022] and reduces confidence in one’s ability to be active [18,23]. Older adults who perceive their neighborhoods as unsafe report higher levels of depressive symptoms, chronic stress, anxiety disorders [24,25], and increased mortality [26,27], all of which are well-established risk factors for chronic conditions, owing to their negative impact on cardiovascular health, immune function, and sleep quality [28,29]. The adverse effects of perceived neighborhood safety on health remain significant even in longitudinal studies, underscoring their long-term impact on older adults [30].

Perceptions of neighborhood safety are often influenced by knowledge of or personal exposure to, crime [31]. The adverse impacts may be particularly severe for older persons who are victims of violent crimes, with crime victimhood negatively affecting their physical [3234] and psychological health [3539]. Research has consistently shown that both short- and long-term exposure to crime in one’s community affects health [7,32,33,40,41]. Crime victimhood can trigger mental health problems such as depression, PTSD, and anxiety [3537], which are significant risk factors for chronic conditions, such as heart disease, diabetes, stroke, osteoporosis, and Alzheimer’s disease [4244]. It can also lead to behavioral changes [45], including social withdrawal [46,47], reduced physical activity [2022], and sleep disturbances [36,48], all of which are known risk factors for chronic conditions including heart diseases, obesity, and musculoskeletal disorders [49]. Psychological distress from crime victimhood can result in unhealthy coping mechanisms [36,50], including smoking, excessive alcohol consumption, and overeating, which further increase the risk of chronic conditions [49,51,52].

Associations between unsafe neighborhoods and multimorbidity have been observed globally. In the U.S, a study conducted in Tennessee found that higher levels of neighborhood crime were significantly associated with the spatial clustering of chronic illnesses [53]. A recent systematic scoping review of 72 studies across several countries, including the United States, the United Kingdom, Canada, Australia, and South Africa, found that unfavorable neighborhood traits, including neighborhood unsafety, were linked to higher rates of multimorbidity [54]. This review found that neighborhood insecurity contributes to multimorbidity through chronic stress, reduced access to health care, limited opportunities for physical activity, and other harmful environmental exposures [54]. Importantly, studies across both urban and rural settings have affirmed the role of neighborhood safety [9,55] and cohesion in shaping health globally [9,56].

Most studies investigating the relationship between neighborhood environments and chronic diseases have been conducted in developed countries. Research specifically targeting older adults in India is limited. Few studies have investigated the association between perceived neighborhood safety and diverse health outcomes, including sleep quality [57] and depression [43,58], among older Indians. Despite growing interest in the health implications of neighborhood conditions, few studies in India have examined these relationships in the context of chronic conditions and multimorbidity among older adults, especially focusing on both perceived safety and direct crime exposure.

As per the Crime in India – 2022 report published by the National Crime Records Bureau (NCRB), the overall crime rate in India declined slightly from 445.9 per 100,000 population in 2021 to 422.2 in 2022 [59,60]. That said, there was an increase in certain types of crime. Crimes against older adults, for instance, went up by 9% in 2022 compared with the previous year [59,60]. A recent study found that crimes such as theft, burglary, and fraud targeting older Indians have increased in large metropolitan cities such as Delhi, Mumbai, Chennai, Hyderabad, and Bengaluru [61]. Factors such as physical vulnerability, social isolation, cognitive decline, and economic challenges may contribute to older Indians’ higher susceptibility to crime [62,63]. The shift from joint family systems to nuclear families due to modernization and urbanization [64] is likely to exacerbate this issue, leading to increased social isolation and reduced familial support for older adults. With fewer extended family members available for support [64], present and future cohorts of older Indians may endure the risk of becoming increasingly isolated [65] and dependent on their immediate environments for social interaction and assistance.

The potential for increased reliance on one’s immediate surroundings highlights the importance of a safe and supportive environment. Given India’s rapidly aging population, high rates of violent crimes [66], and rising burden of chronic disease [2,67,68], this study aimed to examine the association between perceived neighborhood safety, crime victimization, and the prevalence of chronic conditions and multimorbidity among older adults in India.

We also considered the extent to which the associations between neighborhood contexts and chronic conditions, as well as multimorbidity, were moderated by functional disabilities. The press-competence model [69] posits that human behavior and function result from the interaction between an individual’s competencies and the environmental demands or “press.” As individual competence decreases with age, older adults are more susceptible to environmental effects [70]. Choi et al. (2018) applied this model and found that older adults who viewed their neighborhoods as unsafe reported poorer psychological health, with the effect especially pronounced among those with functional limitations [12]. Functional disabilities, defined as difficulties in ADLs and IADLs, can restrict mobility and physical activity [71], a restriction worsened by unsafe neighborhoods [2022], leading to increased chronic conditions [28,29]. These limitations also heighten social isolation [72,73], exacerbated by perceived neighborhood unsafety [46,47], compounding mental health, and chronic disease issues. Access to healthcare may also become more challenging in unsafe areas [74], delaying treatment and management of chronic conditions. Additionally, functional limitations may impair older adults’ ability to respond to threats in unsafe environments [75], intensifying psychological and physical stress and further increasing the risk of chronic conditions. Overall, the combined stress of functional limitations and unsafe environment can increase the risk of developing chronic conditions. An additional objective of this study was to evaluate the degree to which the associations between neighborhood safety, crime victimization, chronic conditions, and multimorbidity were moderated by difficulties in ADLs and IADLs.

Methods

Data and sample

The data were drawn from the World Health Organization’s (WHO) Study on Global AGEing and Adult Health (SAGE), India wave-2, conducted in 2015. The data were accessed for research purposes on 1 September 2024 and at no point did the authors have access to personal identifiable information. This wave covered six diverse states of India, each representing a different region: Assam (Northeast), Karnataka (South), Maharashtra (West), Rajasthan (North), Uttar Pradesh (Central), and West Bengal (East). This study included a comprehensive sample of 9,116 respondents aged 18 years and above. SAGE Wave-2 in India was a follow-up to SAGE Wave-1, maintaining the same primary sampling units (PSUs) and households initially covered by the WHO World Health Survey (WHS) in 2003. In rural areas, a two-stage sampling process was employed, with villages as PSUs and households as secondary stage units (SSUs). In urban areas, a three-stage sampling process was utilized, involving the sequential selection of wards, census enumeration blocks, and households. The number of households selected was proportional to the respective state populations and was distributed across urban and rural areas. The Wave-2 study included 1,998 respondents aged 18–49 years and 7,118 older adults aged ≥ 50 years. In this study, we focused on 7,118 respondents aged ≥ 50 years. In the multivariable models, there were only 48 missing cases, which were handled using list-wise deletion.

Ethics statement

This study involved secondary analysis of publicly available data from the World Health Organization’s SAGE Wave 2. The dataset was accessed directly from the International Institute for Population Sciences (IIPS), Mumbai on 20 April 2023. Ethical approval for primary data collection was obtained by the original investigators from the Institutional Review Board of IIPS, and informed consent was obtained from all participants at the time of data collection. As the dataset was de-identified and publicly accessible, no additional ethical approval was required for this secondary analysis. The authors did not have access to any personally identifiable information.

Outcome variables

Chronic diseases refer to self-reported physician diagnoses of diseases such as hypertension, diabetes, stroke, arthritis, angina, asthma, and lung disease. The variable “number of chronic diseases” was created based on the presence of specific diseases. In this study, multimorbidity referred to the presence of two or more chronic diseases in older adults.

Independent variables

Neighborhood safety was evaluated using two survey questions adopted from the World Bank’s Integrated Questionnaire for the Measurement of Social Capital [76]: [1] “In general, how safe do you feel from crime and violence when you are alone at home?” and [2] “How safe do you feel when walking down your street alone after dark?” (r = 0.65). These items have been used to assess neighborhood safety in various countries including India [43,77]. The responses were on a Likert scale (completely safe, very safe, moderately safe, slightly safe, and not safe at all). We reverse-coded the items and created a summary scale for neighborhood safety ranging from 0 to10, with a higher value reflecting a greater sense of neighborhood safety.

Crime exposure was measured by a single item, “In the last 12 months, have you or anyone in your household been the victim of a violent crime, such as assault or mugging?” The responses were yes or no.

Moderators

Activities of daily living (ADLs) and instrumental activities of daily living (IADLs) were self-reported. In the SAGE survey, participants were asked to report difficulty in performing particular activities in the last 30 days on a five-point scale (none, mild, moderate, severe, and extreme). In this study, severe and extreme difficulties were combined. The ADLs included getting up from lying down, walking, standing for long, carrying things, eating, bathing, dressing, using the toilet, and transferring and concentrating for approximately 10 minutes (Cronbach’s alpha = 0.78). IADLs included using private/public transport, carrying out household responsibilities, joining community functions, doing day-to-day work, and getting out of the household (Cronbach’s alpha = 0.76). ADL and IADL difficulties were recoded as two dichotomous, yes or no variables and participants who reported severe or extreme difficulty in performing any ADL and IADL were coded as “yes” and otherwise “no.” For the sensitivity analysis, we categorized moderate, severe, and extreme difficulties as “yes,” and all other responses as “no”.

Covariates

Based on the aforementioned studies, several sociodemographic and mental health-related variables were selected and included in the current analysis as control factors. The covariates included age, grouped into four categories: 50–59, 60–69, 70–79, and ≥ 80 years; sex, categorized as male or female; and educational level, classified as no education, less than primary, primary, secondary, and higher education. Current marital status was classified as married and unmarried (including widowed, never married, separated, or divorced). Additionally, given the impact of sleep and mental health on chronic conditions, we controlled sleep quality and the self-reported prevalence of depression among participants. Sleep quality was assessed using the question “Please rate the quality of your sleep last night. Was it very good, good, moderate, poor, or very poor?” Poor and very poor were recoded as poor and otherwise good. Prevalence of depression was assessed using the question, “Have you ever been diagnosed with depression?” with response as yes and no.

The household wealth index was calculated based on a detailed list of household assets and amenities, such as durable goods, housing characteristics (type of floors, walls, and cooking stoves), and access to improved water, sanitation, and cooking fuel. Principal component analysis was used to create the wealth index and divided it into five quintiles, with the lowest quintile representing the poorest households and the highest quintile representing the wealthiest households [78]. Religious groups included Hindus, Muslims, and others, while social groups comprised scheduled castes and scheduled tribes (both socioeconomically most disadvantaged) and others. The places of residence were classified as urban or rural, and the states included in the study were Assam, Karnataka, Maharashtra, Rajasthan, Uttar Pradesh, and West Bengal.

Statistical analysis

In this study, descriptive statistics were reported to present the sample distribution and mean scores of the number of chronic conditions, along with standard deviation (SD) and percentage prevalence of multimorbidity across the explanatory variables. Linear and logistic regression models were used to fulfil the study objectives. In addition, we used interaction terms to examine the moderating role of ADL/IADL disabilities on the observed associations. In the multivariable analyses, we used different models to capture the effects of individual and household/community-related variables: Model 1 was adjusted for individual-level variables such as ADL/IADL difficulty, age, sex, education, marital status, sleep quality, and depression; model 2 was additionally adjusted for household and community-related variables such as household wealth quintile, religion, caste, place of residence, and states; and interaction models were adjusted for all the selected variables.

The results were presented as adjusted beta coefficients from linear regression models and odds ratios (OR) from logistic regression models, each with corresponding 95% confidence intervals (CIs). Individual weights were used to account for the sampling design and make the estimates nationally representative. Stata version 16 was used for all analyses [79]. The variance inflation factor (VIF) was calculated using Stata to assess multicollinearity among the selected variables, and no evidence of problematic multicollinearity was found, with all VIF values below 5 (see S1 Table). Survey weights were applied in all analyses to account for the complex survey design, enhancing the accuracy and reliability of the population-level estimates.

Results

Table 1 presents the sample characteristics. A little more than half of the sample were females (52.39%), 5.14% were aged 80 + years, and 48.33% had no formal education. The mean score of neighborhood safety (on a scale of 0–10) was 7.72 (SD: 2.05). Approximately 6% of the participants reported that they or someone in their household were victims of a violent crime in the last one year. A total of 37.28% reported ADL difficulty, and 24.91% reported IADL difficulty.

Table 1. Background characteristics of study participants, SAGE- 2015 (n = 7,118).

Variables n (%)/Mean (SD)
Neighborhood safety, Mean (SD) 7.72 (2.05)
Crime victimhood
No 6684 (94.03)
Yes 434 (5.97)
Number of chronic conditions, Mean (SD) 0.61 (0.84)
Multimorbidity
No 5953 (85.16)
Yes 1165 (14.84)
ADL difficulty
No 4456 (62.72)
Yes 2662 (37.28)
IADL difficulty
No 5385 (75.09)
Yes 1733 (24.91)
Age (in years)
50-59 2904 (40.85)
60-69 2585 (36.02)
70-79 1285 (18)
80+ 344 (5.14)
Sex
Male 3337 (47.61)
Female 3781 (52.39)
Level of education
No formal education 3574 (48.33)
Up to primary 1922 (26.68)
Secondary 675 (9.68)
Higher 947 (15.31)
Current marital status
Married 5305 (74.87)
Unmarried 1813 (25.13)
Depression
No 6948 (97.60)
Yes 170 (2.40)
Sleep quality
Good 4,986 (71.50)
Moderate 1,791 (23.98)
Poor 295 (4.24)
Wealth quintile
Poorest 1371 (20.13)
Poor 1304 (17.97)
Middle 1318 (18.06)
Rich 1468 (20.93)
Richest 1657 (22.90)
Religion
Hindu 5966 (85.08)
Muslim 869 (11.91)
Others 279 (3.00)
Social group
Scheduled castes 522 (6.32)
Scheduled tribes 1168 (14.68)
Other backward classes 3313 (49.56)
Others 2115 (29.44)
Place of residence
Urban 1412 (28.48)
Rural 5606 (71.52)
States
Assam 723 (5.06)
Karnataka 872 (11.21)
Maharashtra 1176 (21.14)
Rajasthan 1456 (12.2)
Uttar Pradesh 1534 (32.27)
West Bengal 1357 (18.13)

N: Unweighted counts; % Weighted percentages to account for sampling design; ADL: Activities of daily living; IADL: Instrumental ADL.

Table 2 presents the bivariate associations of neighborhood safety, crime exposure, ADL/IADL difficulty, and other background characteristics with the number of chronic conditions and multimorbidity. Overall, the mean number of chronic conditions among older adults was 0.66 (SD: 0.86), and 14.84% of the older adults had multimorbidity in this study. Neighbourhood safety was significantly negatively correlated with the number of chronic conditions (r = -0.09) and multimorbidity (r = -0.06). Older adults with crime exposure and ADL/IADL difficulties had a higher prevalence of chronic conditions and multimorbidity. Older adults in the 80 + years age group, those who were currently unmarried, those with higher levels of education, belonging to the higher wealth quintile, and residing in urban areas had a higher number of chronic conditions and multimorbidity. In addition, older adults with poor sleep quality and depression had higher numbers of chronic conditions and multimorbidity.

Table 2. Mean estimates of number of chronic conditions and prevalence of multimorbidity by neighborhood safety, crime victimhood and other background variables among older adults, SAGE- 2015.

Variables Number of chronic conditions Multimorbidity
Mean (SD) n (%)
Neighborhood safety$ *** ***
Crime victimhood ** *
No 0.66 (0.86) 1076 (14.71)
Yes 0.77 (0.88) 88 (17.68)
ADL difficulty *** ***
No 0.55 (0.79) 555 (11.41)
Yes 0.85 (0.94) 610 (20.60)
IADL difficulty *** ***
No 0.6 (0.82) 762 (12.60)
Yes 0.84 (0.95) 403 (21.59)
Age (in years) *** ***
50-59 0.56 (0.79) 373 (11.08)
60-69 0.71 (0.89) 472 (17.13)
70-79 0.75 (0.9) 246 (17.56)
80+ 0.82 (0.95) 74 (19.11)
Sex * #
Male 0.64 (0.87) 516 (14.31)
Female 0.69 (0.86) 649 (15.32)
Level of education *** ***
No formal education 0.58 (0.8) 468 (11.10)
Up to primary 0.72 (0.91) 367 (18.32)
Secondary 0.8 (0.9) 135 (16.85)
Higher 0.76 (0.93) 195 (19.29)
Current marital status ** **
Married 0.64 (0.85) 816 (14.21)
Unmarried 0.73 (0.89) 327 (16.90)
Depression *** ***
No 0.59 (0.83) 1,053 (13.98)
Yes 1.90 (0.78) 112 (64.32)
Sleep quality *** ***
Good 0.56 (0.82) 761 (13.40)
Moderate 0.69 (0.85) 320 (16.75)
Poor 1.03 (1.01) 79 (28.83)
Wealth quintile *** ***
Poorest 0.5 (0.77) 159 (10.11)
Poor 0.6 (0.83) 185 (11.75)
Middle 0.64 (0.86) 198 (13.36)
Rich 0.67 (0.82) 233 (14.60)
Richest 0.86 (0.95) 390 (22.80)
Religion ** *
Hindu 0.65 (0.85) 949 (14.32)
Muslim 0.74 (0.92) 168 (17.47)
Others 0.76 (0.92) 48 (19.33)
Social group ** **
Scheduled castes 0.52 (0.78) 61 (11.20)
Scheduled tribes 0.63 (0.84) 172 (12.84)
Other backward classes 0.67 (0.87) 556 (15.20)
Others 0.7 (0.87) 376 (16.01)
Place of residence *** ***
Urban 0.87 (0.95) 370 (19.83)
Rural 0.61 (0.83) 795 (12.85)
States *** ***
Assam 0.92 (0.94) 183 (26.08)
Karnataka 0.75 (0.89) 164 (19.97)
Maharashtra 0.66 (0.87) 190 (14.53)
Rajasthan 0.69 (0.85) 237 (17.18)
Uttar Pradesh 0.38 (0.69) 127 (7.58)
West Bengal 0.77 (0.9) 264 (20.23)
Total 0.66 (0.86) 1165 (14.84)

SD: Standard deviation; n: Unweighted counts; Means and percentages are weighted to account for sampling design; p-values for number of chronic conditions are based on ANOVA test and p-values for multimorbidity are based on Chi-square test; $ corresponding p-values for neighborhood safety are based on Pearson correlations; *** p < 0.001, ** p < 0.01, * p < 0.05, # p < 0.10; ADL: Activities of daily living; IADL: Instrumental ADL.

Table 3 presents the multivariable linear and logistic regression estimates of the number of chronic conditions and multimorbidity among older adults based on neighborhood safety, crime exposure, and other background characteristics. After adjustment for socioeconomic, demographic, and mental health-related variables, older adults with improved neighborhood safety had a lower number of chronic conditions (beta: -0.03, CI: -0.04, -0.01) and lower odds of multimorbidity (OR: 0.95, CI: 0.91, 0.99). Older adults with crime exposure had a higher number of chronic conditions (beta: 0.10, CI: 0.02, 0.19) than those who did not. Moreover, older adults with higher education and those belonging to the highest household wealth quintile had a greater number of chronic conditions (higher education: beta: 0.19, 95% CI: 0.10, 0.28; richest: beta: 0.28, 95% CI: 0.20, 0.36) and higher odds of multimorbidity (higher education: OR: 2.11, 95% CI: 1.54, 2.89; richest: OR: 2.17, 95% CI: 1.59, 2.97) compared to those with no formal education and belonging to the poorest wealth quintile, respectively. Those residing in rural areas had a lower number of chronic conditions (beta: -0.07, 95% CI: -0.14, -0.01) and lower odds of multimorbidity (OR: 0.75, 95% CI: 0.60, 0.93) than their peers from urban areas. Likewise, those reporting depression and poor sleep quality had more chronic conditions (depression: beta: 1.16, 95% CI: 1.03, 1.29; poor sleep: beta: 0.28, 95% CI: 0.10, 0.45) and greater odds of multimorbidity (depression: OR: 9.91, 95% CI: 6.52, 15.08; poor sleep: OR: 1.73, 95% CI: 1.14, 2.63) than those without depression and those with good sleep quality.

Table 3. Regression estimates of number of chronic conditions and multimorbidity by background variables among older adults SAGE- 2015.

Variables Number of chronic conditions (beta coefficients) Multimorbidity (odds ratios) Number of chronic conditions (beta coefficients) Multimorbidity (odds ratios)
Model 1 Model 2 Model 1 Model 2 Interaction models
Neighborhood safety -0.04*** (-0.05, -0.03) -0.03*** (-0.04, -0.01) 0.92*** (0.89, 0.96) 0.95* (0.91, 0.99)
Crime victimhood
No Ref. Ref. Ref. Ref.
Yes 0.08 (-0.00, 0.17) 0.10* (0.02, 0.19) 1.18 (0.88, 1.59) 1.23 (0.90, 1.68)
ADL difficulty
No Ref. Ref. Ref. Ref.
Yes 0.19*** (0.13, 0.25) 0.22*** (0.16, 0.27) 1.65*** (1.35, 2.02) 1.89*** (1.54, 2.32)
IADL difficulty
No Ref. Ref. Ref. Ref.
Yes 0.07* (0.00, 0.13) 0.12*** (0.06, 0.18) 1.31* (1.06, 1.62) 1.54*** (1.23, 1.92)
Age (in years)
50-59 Ref. Ref. Ref. Ref.
60-69 0.15*** (0.09, 0.21) 0.15*** (0.10, 0.21) 1.61*** (1.31, 1.99) 1.65*** (1.34, 2.04)
70-79 0.17*** (0.09, 0.24) 0.16*** (0.09, 0.23) 1.57** (1.19, 2.06) 1.51** (1.14, 2.00)
80+ 0.18** (0.05, 0.30) 0.13* (0.01, 0.26) 1.64* (1.10, 2.43) 1.45 (0.96, 2.19)
Sex
Male Ref. Ref. Ref. Ref.
Female 0.14*** (0.09, 0.20) 0.09** (0.03, 0.14) 1.57*** (1.27, 1.94) 1.32* (1.07, 1.62)
Level of education
No formal education Ref. Ref. Ref. Ref.
Up to primary 0.22*** (0.16, 0.29) 0.14*** (0.08, 0.20) 2.37*** (1.89, 2.97) 1.93*** (1.55, 2.42)
Secondary 0.31*** (0.23, 0.39) 0.19*** (0.11, 0.28) 2.47*** (1.81, 3.36) 1.76** (1.25, 2.46)
Higher 0.35*** (0.26, 0.44) 0.19*** (0.10, 0.28) 3.31*** (2.50, 4.37) 2.11*** (1.54, 2.89)
Current marital status
Married Ref. Ref. Ref. Ref.
Unmarried -0.02 (-0.08, 0.04) -0.03 (-0.08, 0.03) 1.04 (0.84, 1.28) 1.00 (0.81, 1.25)
Depression
No Ref. Ref. Ref. Ref.
Yes 1.24*** (1.10, 1.38) 1.16*** (1.03, 1.29) 11.07*** (7.41, 16.54) 9.91*** (6.52, 15.08)
Sleep quality
Good Ref. Ref. Ref. Ref.
Moderate 0.09*** (0.04, 0.15) 0.06* (0.01, 0.11) 1.21 (1.00, 1.46) 1.11 (0.91, 1.35)
Poor 0.35*** (0.17, 0.53) 0.28** (0.10, 0.45) 2.01** (1.32, 3.05) 1.73** (1.14, 2.63)
Wealth quintile
Poorest Ref. Ref.
Poor 0.01 (-0.05, 0.07) 0.99 (0.74, 1.33)
Middle 0.01 (-0.05, 0.08) 1.08 (0.80, 1.47)
Rich 0.10** (0.03, 0.17) 1.29 (0.94, 1.77)
Richest 0.28*** (0.20, 0.36) 2.17*** (1.59, 2.97)
Religion
Hindu Ref. Ref.
Muslim 0.08* (0.01, 0.16) 1.46** (1.13, 1.89)
Others 0.11 (-0.03, 0.25) 1.09 (0.71, 1.68)
Social group
Scheduled castes Ref. Ref.
Scheduled tribes 0.07 (-0.01, 0.16) 1.21 (0.82, 1.80)
Other backward classes 0.13** (0.05, 0.21) 1.31 (0.91, 1.90)
Others 0.10* (0.01, 0.18) 1.19 (0.81, 1.75)
Place of residence
Urban Ref. Ref.
Rural -0.07* (-0.14, -0.01) 0.75** (0.60, 0.93)
States
Assam Ref. Ref.
Karnataka -0.09 (-0.19, 0.01) 0.76 (0.56, 1.05)
Maharashtra -0.26*** (-0.35, -0.16) 0.53*** (0.38, 0.73)
Rajasthan -0.18*** (-0.27, -0.09) 0.64** (0.47, 0.86)
Uttar Pradesh -0.49*** (-0.58, -0.40) 0.24*** (0.17, 0.32)
West Bengal -0.11* (-0.20, -0.02) 0.67** (0.51, 0.89)
Neighborhood safety X No ADL difficulty -0.04*** (-0.05, -0.03) 0.89*** (0.85, 0.94)
Neighborhood safety X Yes ADL difficulty -0.01 (-0.02, 0.00) 0.99 (0.95, 1.04)
Neighborhood safety X No IADL difficulty -0.03*** (-0.05, -0.02) 0.92*** (0.88, 0.96)
Neighborhood safety X Yes IADL difficulty -0.01 (-0.02, 0.01) 1.01 (0.97, 1.06)
No crime victimhood X No ADL difficulty Ref. Ref.
No crime victimhood X Yes ADL difficulty 0.26*** (0.21, 0.31) 2.17*** (1.80, 2.63)
Yes crime victimhood X No ADL difficulty 0.01 (-0.09, 0.10) 0.74 (0.46, 1.20)
Yes crime victimhood X Yes ADL difficulty 0.49*** (0.34, 0.64) 3.68*** (2.42, 5.61)
No crime victimhood X No IADL difficulty Ref. Ref.
No crime victimhood X Yes IADL difficulty 0.23*** (0.17, 0.29) 2.13*** (1.74, 2.61)
Yes crime victimhood X No IADL difficulty 0.04 (-0.05, 0.14) 1.08 (0.71, 1.64)
Yes crime victimhood X Yes IADL difficulty 0.51*** (0.34, 0.69) 3.52*** (2.15, 5.77)

Ref. Referent group; *** p < 0.001, ** p < 0.01, * p < 0.05; Model 1 is adjusted for all the individual-level variables such as ADL/IADL difficulty, age, sex, education, marital status, sleep quality and depression; Model 2 is additionally adjusted for household and community-related variables such as household wealth quintile, religion, caste, place of residence and states; Interaction models are adjusted for all the selected variables.

Table 3 presents the interaction between ADL/IADL difficulties and neighborhood safety, crime exposure on the number of chronic conditions, and multimorbidity among older adults. Those with safe neighborhoods but with ADL/IADL difficulties had higher levels of chronic conditions and multimorbidity compared to those without ADL/IADL difficulties. Older adults with crime exposure and ADL/IADL difficulties had higher levels of chronic conditions and multimorbidity than their peers with no ADL/IADL difficulties.

Discussion

This study explored the associations between perceived neighborhood safety, crime exposure, prevalence of chronic conditions, and multimorbidity among community-dwelling older individuals in India, with a specific focus on the moderating role of functional disabilities measured by difficulties in ADLs and IADLs. Our findings indicate that older Indians who perceive their neighborhoods as unsafe report more chronic conditions and have higher odds of multimorbidity. These findings are consistent with studies from developed nations, where unsafe neighborhoods are linked to increased stress, reduced physical activity, and higher rates of chronic diseases [11,18,23,24,80,81].

Living in unsafe neighborhood can lead to chronic mental distress, which adversely affects cardiovascular and immune function [11,28,82,83]. Fear of crime can limit outdoor movements and physical activity [18,23], thereby increasing the risk of obesity and related chronic ailments [27]. While perceived neighborhood safety can stimulate social interaction and social engagement, perceived unsafety in one’s immediate surroundings can engender powerlessness, mistrust, limited social contact, and increased social isolation [84]. These social stressors, especially mistrust and isolation, can increase the risk of a range of chronic health issues including cardiovascular disease, some cancers, and cognitive decline [8588]. In fact, stress experienced through social disconnection triggers the same areas in the brain that are triggered during physical pain [89,90], underscoring the profound health consequences of living in unsafe or isolating environments.

Our findings also reveal that crime victimhood is adversely associated with an increased number of chronic ailments and multimorbidity, consistent with prior research indicating that crime victimhood can lead to both immediate and long-term health consequences [7,33,40,41]. Exposure to crime can lead to mental health conditions such as depression, anxiety, and PTSD, which may, in turn, contribute to subsequent chronic conditions [36,43,42]. The psychological trauma from victimization may also translate into unhealthy coping mechanisms [36,50], further increasing the risk of chronic diseases [91]. Physiologically, the stress response to victimization, marked by increased levels of cortisol and other stress hormones [29,92,93], can impair immune function and contribute to the onset of chronic disease onset [28,94]. Moreover, victimhood can lead to social withdrawal and isolation [46], reducing social support, and worsening loneliness and depression, both of which are linked to adverse health outcomes [33]. These findings highlight the relevance of broader support systems for mitigating the health consequences of crime victimization among older adults who have experienced crime.

We also observed that the associations between perceived neighborhood safety, crime victimization, chronic conditions, and multimorbidity were stronger among older adults with ADL/IADL limitations. This finding, although based on cross-sectional data, reflects the press-competence model, which suggests that individuals with lower functional competence are more vulnerable to environmental stressors [12]. Older adults with functional limitations may lack the physical and cognitive resources to effectively cope with unsafe surroundings, heightening both psychological and physiological stress. These limitations can hinder their ability to respond to threats and navigate their environment safely, intensify feelings of vulnerability, and trigger stress-related biological processes that promote chronic diseases [82]. Limited mobility can also restrict physical activity, contributing to obesity and related illnesses such as diabetes and cardiovascular disease [95,96]. Moreover, greater dependence on others for daily tasks may engender helplessness and depression, both of which are linked to poor health outcomes [30].

In addition to neighborhood safety and crime exposure, we also observed meaningful associations between sociodemographic characteristics, chronic conditions, and multimorbidity. For instance, higher education levels were associated with more chronic conditions and higher odds of multimorbidity. Individuals who are more educated may have better and more stable access to healthcare and, in turn, be more likely to be formally diagnosed [9799]. It is also possible that those with more education report health conditions more accurately because of their greater health literacy and awareness [100]. Likewise, older Indians in the higher wealth quintiles and urban dwellers reported more diagnosed chronic ailments and endured higher odds of multimorbidity. While this finding may reflect better access to medical professionals and formal diagnoses [101103], it may also indicate growing health burdens among more urbanized and economically advantaged individuals, potentially due to adverse lifestyle factors [67,104]. Moreover, although not statistically significant in multivariable models, unmarried older Indians had slightly higher rates of chronic illness in bivariate analysis, suggesting that the absence of spousal support may play a role in shaping later-life health [105]. These findings underscore the relevance of social and structural locations to health in later life.

Our findings also showed that depression and poor sleep quality are associated with a higher number of chronic conditions and greater odds of multimorbidity. These associations may reflect underlying physiological mechanisms, such as inflammation and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, both of which are implicated in sleep disturbances and mental health disorders [106,107]. Additionally, depression and poor sleep may reduce motivation for health-promoting behaviors [108,109], increase healthcare neglect [110], and increase vulnerability to stress-related illnesses [111], thereby exacerbating physical health conditions.

Public health implications

This study’s findings have significant implications for public health. Although causal relationships cannot be inferred owing to the cross-sectional nature of the data, the observed associations point to several intervention opportunities. Increasing neighborhood safety through community policing, better street lighting, and neighborhood watch programs could improve both perceived and actual safety, thus benefiting older adults’ health. For those who have experienced a crime, access to psychological support and counselling may help reduce adverse effects.

Addressing the needs of older adults with ADL and IADL limitations through home modifications, assistive devices, and support services could help reduce their vulnerability to environmental stressors and improve their overall health. Public awareness campaigns highlighting the impact of crime on older adults’ mental and physical health could encourage greater community involvement in crime prevention initiatives. Finally, strengthening strong social networks within unsafe neighborhoods can build social cohesion, reduce social isolation, and support healthy aging.

Strengths and limitations

To our knowledge, this is the first study to evaluate the link between perceived neighborhood safety, crime victimization, functional limitations, and chronic conditions among older adults in India, a context that is often underrepresented in the literature. The use of a large representative sample improves the generalizability of the findings, whereas considering functional limitations as a moderator provides a nuanced understanding of the interactions between individual capacities and environmental stressors. Moreover, the use of perceptions of neighborhood safety adds to the strengths of this study. Ample evidence links neighborhood environments with morbidity [112]. However, most inferences are based on objective traits measured with administrative data or researcher observations [12,112,113]. Studies using residents’ perceptions of their neighborhoods show inconsistent results, as perceptions are influenced by both observable and unobservable elements [10,12,114,115]. In the present study, we addressed how a perceived neighborhood context, namely, safety within one’s immediate surroundings, is linked to chronic health conditions among older Indians.

Alongside these strengths, we noted some important limitations of our study. First, the cross-sectional design of the study limits its ability to infer causality or even temporality. Second, reliance on self-reported data for chronic conditions may introduce reporting bias. Future studies should incorporate more objective health data. Similarly, although the subjective appraisal of neighborhood safety constitutes a strength of this study, studies replicating our research should consider using both subjective and objective measures of neighborhood safety. Subjective reports of crime victimization among older adults may also be affected by recall bias, perception inaccuracies, social desirability bias, and emotional or psychological factors, leading to over- or under-reporting. Types of crime may also play a role, an aspect that we were unable to consider with these data. Third, although we considered several conceptually relevant covariates, residual bias is always possible. In particular, we did not account for potential confounders, such as social support networks and living arrangements, both of which could influence the observed associations.

Conclusion

Our study highlights the significant connections between perceived neighborhood safety, crime victimization, and the prevalence of chronic diseases and multimorbidity among older individuals in India, with these associations being particularly strong among those with ADL and IADL limitations. These findings suggest a need for far-reaching public health strategies that consider the environmental, social, and individual determinants of health to improve the health and wellness of older Indians. However, given the cross-sectional nature of our data, these associations should be interpreted with caution and further longitudinal research is required to establish causality.

Supporting information

S1 Table. Variance Inflation Factor (VIF) and 1/VIF (tolerance) values of the selected variables.

(DOCX)

pgph.0005151.s001.docx (18.3KB, docx)

Data Availability

The data used for this study is the Study on Global AGEing and Adult Health (SAGE) Wave 2 conducted by the World Health Organization. These data are publicly available on the National Archive of Computerized Data on Aging (NACDA) website https://www.icpsr.umich.edu/web/ICPSR/studies/31381/datadocumentation.

Funding Statement

The author(s) received no specific funding for this work.

References

  • 1.Islam MS, Mondal MNI, Tareque MI, Rahman MA, Hoque MN, Ahmed MM, et al. Correlates of healthy life expectancy in low- and lower-middle-income countries. BMC Public Health. 2018;18. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Kalra A, Jose AP, Prabhakaran P, Kumar A, Agrawal A, Roy A, et al. The burgeoning cardiovascular disease epidemic in Indians - perspectives on contextual factors and potential solutions. Lancet Reg Health Southeast Asia. 2023;12:100156. doi: 10.1016/j.lansea.2023.100156 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Chronic physical conditions, physical multimorbidity, and quality of life among adults aged ≥ 50 years from six low- and middle-income countries. Accessed 2024 June 19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063492/ [DOI] [PMC free article] [PubMed]
  • 4.Abebe F, Schneider M, Asrat B, Ambaw F. Multimorbidity of chronic non-communicable diseases in low- and middle-income countries: a scoping review. J Comorbidity. 2020;10:2235042X20961919. doi: 10.1177/2235042X20961919 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Vos T, Lim SS, Abbafati C, Abbas KM, Abbasi M, Abbasifard M, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet. 2020;396(10258):1204–22. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.Ndubuisi NE. Noncommunicable diseases prevention in low- and middle-income countries: an overview of health in all policies (HiAP). Inq J Med Care Organ Provis Financ. 2021;58. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Boylan JM, Robert SA. Neighborhood SES is particularly important to the cardiovascular health of low SES individuals. Soc Sci Med. 2017;188:60–8. doi: 10.1016/j.socscimed.2017.07.005 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Subramanian SV, Kubzansky L, Berkman L, Fay M, Kawachi I. Neighborhood effects on the self-rated health of elders: uncovering the relative importance of structural and service-related neighborhood environments. J Gerontol Ser B. 2006;61(3):S153-60. [DOI] [PubMed] [Google Scholar]
  • 9.Won J, Lee C, Forjuoh SN, Ory MG. Neighborhood safety factors associated with older adults’ health-related outcomes: a systematic literature review. Soc Sci Med. 2016;165:177–86. [DOI] [PubMed] [Google Scholar]
  • 10.Yen IH, Michael YL, Perdue L. Neighborhood environment in studies of health of older adults: a systematic review. Am J Prev Med. 2009;37(5):455–63. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Kershaw KN, Magnani JW, Diez Roux AV, Camacho-Rivera M, Jackson EA, Johnson AE, et al. Neighborhoods and cardiovascular health: a scientific statement from the American heart association. Circ Cardiovasc Qual Outcomes. 2024;17(1):e000124. doi: 10.1161/HCQ.0000000000000124 [DOI] [PubMed] [Google Scholar]
  • 12.Choi YJ, Matz-Costa C. Perceived neighborhood safety, social cohesion, and psychological health of older adults. Gerontologist. 2018;58(1):196–206. doi: 10.1093/geront/gnw187 [DOI] [PubMed] [Google Scholar]
  • 13.Oyeyemi AL, Kolo SM, Oyeyemi AY, Omotara BA, Yahaya SJ, Sallis JF. Neighborhood environment and quality of life among community-living older adults in Nigeria: the moderating effect of physical activity. Prev Med Rep. 2023;35:102330. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Pickett KE, Pearl M. Multilevel analyses of neighbourhood socioeconomic context and health outcomes: a critical review. J Epidemiol Community Health. 2001;55(2):111–22. doi: 10.1136/jech.55.2.111 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 15.Wu Y-T, Prina AM, Brayne C. The association between community environment and cognitive function: a systematic review. Soc Psychiatry Psychiatr Epidemiol. 2015;50(3):351–62. doi: 10.1007/s00127-014-0945-6 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 16.Buffel T, Donder LD, Phillipson C, Witte ND, Dury S, Verté D. Place attachment among older adults living in four communities in Flanders, Belgium. Hous Stud. 2014;29(6):800–22. [Google Scholar]
  • 17.Wiles JL, Allen RES, Palmer AJ, Hayman KJ, Keeling S, Kerse N. Older people and their social spaces: a study of well-being and attachment to place in Aotearoa New Zealand. Soc Sci Med. 2009;68(4):664–71. [DOI] [PubMed] [Google Scholar]
  • 18.Sun VK, Stijacic Cenzer I, Kao H, Ahalt C, Williams BA. How safe is your neighborhood? Perceived neighborhood safety and functional decline in older adults. J Gen Intern Med. 2012;27(5):541–7. doi: 10.1007/s11606-011-1943-y [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 19.Gill TM, Zang EX, Murphy TE, Leo-Summers L, Gahbauer EA, Festa N, et al. Association between neighborhood disadvantage and functional well-being in community-living older persons. JAMA Intern Med. 2021;181(10):1297–304. doi: 10.1001/jamainternmed.2021.4260 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20.Mendes de Leon CF, Cagney KA, Bienias JL, Barnes LL, Skarupski KA, Scherr PA, et al. Neighborhood social cohesion and disorder in relation to walking in community-dwelling older adults: a multilevel analysis. J Aging Health. 2009;21(1):155–71. doi: 10.1177/0898264308328650 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Sallis JF, King AC, Sirard JR, Albright CL. Perceived environmental predictors of physical activity over 6 months in adults: activity counseling trial. Health Psychol. 2007;26(6):701–9. doi: 10.1037/0278-6133.26.6.701 [DOI] [PubMed] [Google Scholar]
  • 22.Foster S, Knuiman M, Hooper P, Christian H, Giles-Corti B. Do changes in residents’ fear of crime impact their walking? Longitudinal results from RESIDE. Prev Med. 2014;62:161–6. doi: 10.1016/j.ypmed.2014.02.011 [DOI] [PubMed] [Google Scholar]
  • 23.Bennett GG, McNeill LH, Wolin KY, Duncan DT, Puleo E, Emmons KM. Safe to walk? Neighborhood safety and physical activity among public housing residents. PLoS Med. 2007;4(10):1599–606; discussion 1607. doi: 10.1371/journal.pmed.0040306 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24.Robinette JW, Piazza JR, Stawski RS. Neighborhood safety concerns and daily well-being: a national diary study. Wellbeing Space Soc. 2021;2:100047. doi: 10.1016/j.wss.2021.100047 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 25.Frazier C. Perceptions matter: physical neighborhood disadvantage and older adults’ emotional health. Wellbeing Space Soc. 2025;8:100266. doi: 10.1016/j.wss.2025.100266 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 26.Generaal E, Timmermans EJ, Dekkers JEC, Smit JH, Penninx BWJH. Not urbanization level but socioeconomic, physical and social neighbourhood characteristics are associated with presence and severity of depressive and anxiety disorders. Psychol Med. 2019;49(1):149–61. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 27.Henderson H, Child S, Moore S, Moore JB, Kaczynski AT. The influence of neighborhood aesthetics, safety, and social cohesion on perceived stress in disadvantaged communities. Am J Community Psychol. 2016;58(1–2):80–8. doi: 10.1002/ajcp.12081 [DOI] [PubMed] [Google Scholar]
  • 28.Kendall-Tackett K. Psychological trauma and physical health: a psychoneuroimmunology approach to etiology of negative health effects and possible interventions. Psychol Trauma Theory, Res Pract Policy. 2009;1(1):35–48. doi: 10.1037/a0015128 [DOI] [Google Scholar]
  • 29.Seiler A, Fagundes CP, Christian LM. The impact of everyday stressors on the immune system and health. In: Stress challenges and immunity in space. Springer International Publishing; 2019. 71–92. doi: 10.1007/978-3-030-16996-1_6 [DOI] [Google Scholar]
  • 30.Robinette JW, Charles ST, Gruenewald TL. Vigilance at home: longitudinal analyses of neighborhood safety perceptions and health. SSM Popul Health. 2016;2:525–30. doi: 10.1016/j.ssmph.2016.06.004 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 31.Velasquez AJ, Douglas JA, Guo F, Robinette JW. What predicts how safe people feel in their neighborhoods and does it depend on functional status?. SSM - Popul Health. 2021;16:100927. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 32.Rosen T, Makaroun LK, Conwell Y, Betz M. Violence in older adults: scope, impact, challenges, and strategies for prevention. Health Aff (Millwood). 2019;38(10):1630–7. doi: 10.1377/hlthaff.2019.00577 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 33.Tung EL, Johnson TA, O’Neal Y, Steenes AM, Caraballo G, Peek ME. Experiences of community violence among adults with chronic conditions: qualitative findings from Chicago. J Gen Intern Med. 2018;33(11):1913–20. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 34.Stafford M, Chandola T, Marmot M. Association between fear of crime and mental health and physical functioning. Am J Public Health. 2007;97(11):2076–81. doi: 10.2105/AJPH.2006.097154 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 35.Hessel P, Martínez Botero MA, Cuartas J. Acute exposure to violent neighborhood crime and depressive symptoms among older individuals in Colombia. Health Place. 2019;59:102162. [DOI] [PubMed] [Google Scholar]
  • 36.Satchell J, Craston T, Drennan VM, Billings J, Serfaty M. Psychological distress and interventions for older victims of crime: a systematic review. Trauma Violence Abuse. 2023;24(5):3493–512. doi: 10.1177/15248380221130354 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 37.Serfaty M, Ridgewell A, Drennan V, Kessel A, Brewin CR, Leavey G, et al. Helping aged victims of crime (the HAVoC Study): common crime, older people and mental illness. Behav Cogn Psychother. 2016;44(2):140–55. doi: 10.1017/S1352465814000514 [DOI] [PubMed] [Google Scholar]
  • 38.Stafford M, Marmot M. Neighbourhood deprivation and health: does it affect us all equally?. Int J Epidemiol. 2003;32(3):357–66. doi: 10.1093/ije/dyg084 [DOI] [PubMed] [Google Scholar]
  • 39.Pearson AL, Breetzke GD. The association between the fear of crime, and mental and physical wellbeing in New Zealand. Soc Indic Res. 2013;119(1):281–94. doi: 10.1007/s11205-013-0489-2 [DOI] [Google Scholar]
  • 40.Mayne SL, Pool LR, Grobman WA, Kershaw KN. Associations of neighborhood crime with adverse pregnancy outcomes among women in Chicago: analysis of electronic health records from 2009-2013. J Epidemiol Community Health. 2018;72(3):230–6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 41.Sundquist K, Theobald H, Yang M, Li X, Johansson S-E, Sundquist J. Neighborhood violent crime and unemployment increase the risk of coronary heart disease: a multilevel study in an urban setting. Soc Sci Med. 2006;62(8):2061–71. doi: 10.1016/j.socscimed.2005.08.051 [DOI] [PubMed] [Google Scholar]
  • 42.Gray MJ, Acierno R. Symptom presentations of older adult crime victims: description of a clinical sample. J Anxiety Disord. 2002;16(3):299–309. doi: 10.1016/s0887-6185(02)00101-9 [DOI] [PubMed] [Google Scholar]
  • 43.Muhammad T, Meher T, Sekher TV. Association of elder abuse, crime victimhood and perceived neighbourhood safety with major depression among older adults in India: a cross-sectional study using data from the LASI baseline survey (2017-2018). BMJ Open. 2021;11(12):e055625. doi: 10.1136/bmjopen-2021-055625 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 44.Zhang Y, Chen Y, Ma L. Depression and cardiovascular disease in elderly: current understanding. J Clin Neurosci Off J Neurosurg Soc Australas. 2018;47:1–5. [DOI] [PubMed] [Google Scholar]
  • 45.Tan SY, Haining R. Crime victimization and the implications for individual health and wellbeing: a Sheffield case study. Soc Sci Med. 2016;167:128–39. [DOI] [PubMed] [Google Scholar]
  • 46.Tung EL, Hawkley LC, Cagney KA, Peek ME. Social isolation, loneliness, and violence exposure in urban adults. Health Aff (Millwood). 2019;38(10):1670–8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 47.Smith NA, Voisin DR, Yang JP, Tung EL. Keeping your guard up: hypervigilance among urban residents affected by community and police violence. Health Aff Proj Hope. 2019;38(10):1662–9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 48.Clark AE, D’Ambrosio C, Zhu R. Crime victimisation over time and sleep quality. SSM - Popul Health. 2019;7:100401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 49.Huston P. A sedentary and unhealthy lifestyle fuels chronic disease progression by changing interstitial cell behaviour: a network analysis. Front Physiol. 2022;13:904107. doi: 10.3389/fphys.2022.904107 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 50.Reisig MD, Holtfreter K, Turanovic JJ. Criminal victimization, depressive symptoms, and behavioral avoidance coping in late adulthood: the conditioning role of strong familial ties. J Adult Dev. 2018;25(1):13–24. [Google Scholar]
  • 51.Du Y, de Bock GH, Vonk JM, Pham AT, van der Ende MY, Snieder H. Lifestyle factors and incident multimorbidity related to chronic disease: a population-based cohort study. Eur J Ageing. 2024;21(1):37. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 52.Niebuur J, Vonk JM, Du Y, de Bock GH, Lunter G, Krabbe PFM, et al. Lifestyle factors related to prevalent chronic disease multimorbidity: a population-based cross-sectional study. PLoS One. 2023;18(7):e0287263. doi: 10.1371/journal.pone.0287263 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 53.Shin EK, Kwon Y, Shaban-Nejad A. Geo-clustered chronic affinity: pathways from socio-economic disadvantages to health disparities. JAMIA Open. 2019;2(3):317–22. doi: 10.1093/jamiaopen/ooz029 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 54.Zheng C, MacRae C, Rowley-Abel L, Arakelyan S, Abubakar E, Dibben C. The impact of place on multimorbidity: a systematic scoping review. Soc Sci Med. 2024;361:117379. [DOI] [PubMed] [Google Scholar]
  • 55.Finlay J, Westrick AC, Guzman V, Meltzer G. Neighborhood built environments and health in later life: a literature review. J Aging Health. 2025;37(1–2):3–17. doi: 10.1177/08982643231217776 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 56.The role of neighborhood social capital on health and health inequality in rural and urban China. ScienceDirect. 2025 July 25. https://www.sciencedirect.com/science/article/abs/pii/S0091743522000378 [DOI] [PubMed]
  • 57.Muhammad T, Pai M, Kumar A, Lekshmi P, Sekher TV. Associations between neighbourhood safety, social cohesion, sleep quality and sleep duration among older adults in India: findings from the study on global aging and adult health (WHO-SAGE), 2015. Psychogeriatr Off Jpn Psychogeriatr Soc. 2024. [DOI] [PubMed] [Google Scholar]
  • 58.Muhammad T, Thakkar S, Balachandran A. Understanding depression in older Indians using diathesis-stress framework: the role of neighborhood safety and physical and functional health. Int J Geriatr Psychiatry. 2023;38(7):e5961. doi: 10.1002/gps.5961 [DOI] [PubMed] [Google Scholar]
  • 59.Crime in India table content. National crime records bureau. Accessed 2025 June 28. https://www.ncrb.gov.in/crime-in-india-table-content.html?year=2022
  • 60.Crime in India. Accessed 2025 June 28. https://www.ncrb.gov.in/crime-in-india.html
  • 61.Sarkar S. Crime against senior citizens in metropolitan cities in India: trend, effects and government initiatives. Vidya - J Gujarat Univ. 2025;4(1):18–28. [Google Scholar]
  • 62.Patel AB. Effect of crime on the wellbeing of the elderly: a content analysis study of Indian elderly. Int J Criminol Sociol Theory. 2013;6(2):1138–49. [Google Scholar]
  • 63.Jaggi P, Saleem Z. Ageing population of urban India & psychological well-being issues. Int J Soc Sci. 2020;9(3):169–84. [Google Scholar]
  • 64.Chandra V. Changing landscape of indian family. In: Contemporary perspectives in family research. Emerald Publishing Limited; 2024. 65–76. doi: 10.1108/s1530-353520240000026004 [DOI] [Google Scholar]
  • 65.Dewari AS, Chakrabarti D, Goswami V, Chandel S. Loneliness and living: the trigger effect of living arrangements and self-reported health in adults 45 – a LASI cross-sectional study. J Hum Behav Soc Environ. 0(0):1–19. [Google Scholar]
  • 66.Ohlan R. Are regional crime rates in India natural?. Crime Law Soc Change. 2019;73. [Google Scholar]
  • 67.Jana A, Chattopadhyay A. Prevalence and potential determinants of chronic disease among elderly in India: rural-urban perspectives. PLoS One. 2022;17(3):e0264937. doi: 10.1371/journal.pone.0264937 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 68.Patel P, Muhammad T, Sahoo H. The burden of disease-specific multimorbidity among older adults in India and its states: evidence from LASI. BMC Geriatr. 2023;23(1):53. doi: 10.1186/s12877-023-03728-1 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 69.Lawton MP, Nahemow L. Ecology and the aging process. In: The psychology of adult development and aging. Washington, DC, US: American Psychological Association; 1973. 619–74. [Google Scholar]
  • 70.Leiva-Caro JA, Salazar-González BC, Gallegos-Cabriales EC, Gómez-Meza MV, Hunter KF. Connection between competence, usability, environment and risk of falls in elderly adults. Rev Lat Am Enfermagem. 2015;23(6):1139–48. doi: 10.1590/0104-1169.0331.2659 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 71.Fuchs J, Gaertner B, Prütz F. Limitations in activities of daily living and support needs – Analysis of GEDA 2019/2020-EHIS. J Health Monit. 2022;7(1):6–25. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 72.Pavela G. Functional status and social contact among older adults. Res Aging. 2015;37(8):815–36. doi: 10.1177/0164027514566091 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 73.Pan C, Yu L, Cao N. Reciprocal and dynamic associations between social isolation, loneliness, and disability among Chinese older adults. J Am Med Dir Assoc. 2024;:104975. [DOI] [PubMed] [Google Scholar]
  • 74.Szanton SL, Roth J, Nkimbeng M, Savage J, Klimmek R. Improving unsafe environments to support aging independence with limited resources. Nurs Clin North Am. 2014;49(2):133–45. doi: 10.1016/j.cnur.2014.02.002 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 75.Suzuki R, Blackwood J, Webster NJ, Shah S. Functional limitations and perceived neighborhood walkability among urban dwelling older adults. Front Public Health. 2021;9:675799. doi: 10.3389/fpubh.2021.675799 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 76.Grootaert C. Measuring social capital: an integrated questionnaire. World Bank Publications; 2004. [Google Scholar]
  • 77.Hill TD, Trinh HN, Wen M, Hale L. Perceived neighborhood safety and sleep quality: a global analysis of six countries. Sleep Med. 2016;18:56–60. doi: 10.1016/j.sleep.2014.12.003 [DOI] [PubMed] [Google Scholar]
  • 78.Arokiasamy P, Selvamani Y, Jotheeswaran AT, Sadana R. Socioeconomic differences in handgrip strength and its association with measures of intrinsic capacity among older adults in six middle-income countries. Sci Rep. 2021;11(1):19494. doi: 10.1038/s41598-021-99047-9 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 79.StataCorp. Stata statistical software: release 15. College Station, TX: StataCorp LLC; 2017. [Google Scholar]
  • 80.Cutrona CE, Wallace G, Wesner KA. Neighborhood characteristics and depression. Curr Dir Psychol Sci. 2006;15(4):188–92. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 81.Freedman VA, Grafova IB, Rogowski J. Neighborhoods and chronic disease onset in later life. Am J Public Health. 2011;101(1):79–86. doi: 10.2105/AJPH.2009.178640 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 82.Seiler A, von Känel R, Slavich GM. The psychobiology of bereavement and health: a conceptual review from the perspective of social signal transduction theory of depression. Front Psychiatry. 2020;11:565239. doi: 10.3389/fpsyt.2020.565239 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 83.Klopack ET, Crimmins EM, Cole SW, Seeman TE, Carroll JE. Social stressors associated with age-related T lymphocyte percentages in older US adults: evidence from the US health and retirement study. Proc Natl Acad Sci U S A. 2022;119(25):e2202780119. doi: 10.1073/pnas.2202780119 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 84.Ross CE, Jang SJ. Neighborhood disorder, fear, and mistrust: the buffering role of social ties with neighbors. Am J Community Psychol. 2000;28(4):401–20. doi: 10.1023/a:1005137713332 [DOI] [PubMed] [Google Scholar]
  • 85.Cardona M, Andrés P. Are social isolation and loneliness associated with cognitive decline in ageing?. Front Aging Neurosci. 2023;15:1075563. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 86.Read S, Comas-Herrera A, Grundy E. Social isolation and memory decline in later-life. J Gerontol Ser B. 2020;75(2):367–76. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 87.Albasheer O, Abdelwahab SI, Zaino MR, Altraifi AAA, Hakami N, El-Amin EI, et al. The impact of social isolation and loneliness on cardiovascular disease risk factors: a systematic review, meta-analysis, and bibliometric investigation. Sci Rep. 2024;14(1):12871. doi: 10.1038/s41598-024-63528-4 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 88.Kraav SL, Lehto SM, Kauhanen J, Hantunen S, Tolmunen T. Loneliness and social isolation increase cancer incidence in a cohort of Finnish middle-aged men. A longitudinal study. Psychiatry Res. 2021;299:113868. [DOI] [PubMed] [Google Scholar]
  • 89.Eisenberger NI, Lieberman MD, Williams KD. Does rejection hurt? An FMRI study of social exclusion. Science. 2003;302(5643):290–2. doi: 10.1126/science.1089134 [DOI] [PubMed] [Google Scholar]
  • 90.Medeiros P, Medeiros AC, Coimbra JPC, de Paiva Teixeira LEP, Salgado-Rohner CJ, da Silva JA. Physical, emotional, and social pain during COVID-19 pandemic-related social isolation. Trends Psychol. 2022;1–29. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 91.Zhang Y, Chen Y, Ma L. Depression and cardiovascular disease in elderly: current understanding. J Clin Neurosci. 2018;47:1–5. [DOI] [PubMed] [Google Scholar]
  • 92.Chu B, Marwaha K, Sanvictores T, Awosika AO, Ayers D. Physiology, stress reaction. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024. http://www.ncbi.nlm.nih.gov/books/NBK541120/ [PubMed] [Google Scholar]
  • 93.Adamo SA. The effects of stress hormones on immune function may be vital for the adaptive reconfiguration of the immune system during fight-or-flight behavior. Integr Comp Biol. 2014;54(3):419–26. [DOI] [PubMed] [Google Scholar]
  • 94.Collins RE, Marrone DF. Scared sick: relating fear of crime to mental health in older adults. Sage Open. 2015;5(3). [Google Scholar]
  • 95.Qin L, Knol MJ, Corpeleijn E, Stolk RP. Does physical activity modify the risk of obesity for type 2 diabetes: a review of epidemiological data. Eur J Epidemiol. 2010;25(1):5–12. doi: 10.1007/s10654-009-9395-y [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 96.McCarthy MM, Wackers FJT h, Davey J, Chyun DA. Physical inactivity and cardiac events: an analysis of the detection of ischemia in asymptomatic diabetics (DIAD) study. J Clin Transl Endocrinol. 2017;9:8–14. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 97.Link BG, Phelan J. Social conditions as fundamental causes of disease. J Health Soc Behav. 1995;Spec No:80–94. [PubMed] [Google Scholar]
  • 98.Cundiff JM, Boylan JM, Muscatell KA. The pathway from social status to physical health: taking a closer look at stress as a mediator. Curr Dir Psychol Sci. 2020;29(2):147–53. [Google Scholar]
  • 99.Hout M. Social and economic returns to college education in the United States. Annu Rev Sociol. 2012;38(1):379–400. [Google Scholar]
  • 100.Raghupathi V, Raghupathi W. The influence of education on health: an empirical assessment of OECD countries for the period 1995–2015. Arch Public Health. 2020;78(1):20. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 101.Mackenbach JP, Stirbu I, Roskam A-JR, Schaap MM, Menvielle G, Leinsalu M, et al. Socioeconomic inequalities in health in 22 European countries. N Engl J Med. 2008;358(23):2468–81. doi: 10.1056/NEJMsa0707519 [DOI] [PubMed] [Google Scholar]
  • 102.Basu J. Research on disparities in primary health care in rural versus urban areas: select perspectives. Int J Environ Res Public Health. 2022;19(12):7110. doi: 10.3390/ijerph19127110 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 103.Das J, Kundu S, Hossain B. Rural-urban difference in meeting the need for healthcare and food among older adults: evidence from India. BMC Public Health. 2023;23(1):1231. doi: 10.1186/s12889-023-16126-4 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 104.Venkatesh U, Grover A, Vignitha B, Ghai G, Malhotra S, Kishore J, et al. Urban-rural disparities in blood pressure and lifestyle risk factors of hypertension among Indian individuals. J Family Med Prim Care. 2022;11(9):5746–56. doi: 10.4103/jfmpc.jfmpc_573_22 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 105.Carr D, Utz R. Late-life widowhood in the United States: new directions in research and theory. Ageing Int. 2001. Dec 1;27(1):65–88. [Google Scholar]
  • 106.Du X, Pang TY. Is dysregulation of the HPA-axis a core pathophysiology mediating co-morbid depression in neurodegenerative diseases?. Front Psychiatry. 2015;6:32. doi: 10.3389/fpsyt.2015.00032 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 107.Suarez EC, Goforth H. Sleep and inflammation: a potential link to chronic diseases. 2010. Accessed 2025 June 29. https://psycnet.apa.org/record/2009-13365-003
  • 108.Kaar JL, Luberto CM, Campbell KA, Huffman JC. Sleep, health behaviors, and behavioral interventions: reducing the risk of cardiovascular disease in adults. World J Cardiol. 2017;9(5):396–406. doi: 10.4330/wjc.v9.i5.396 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 109.Chang C-F, Lin M-H, Wang J, Fan J-Y, Chou L-N, Chen M-Y. The relationship between geriatric depression and health-promoting behaviors among community-dwelling seniors. J Nurs Res. 2013;21(2):75–82. doi: 10.1097/jnr.0b013e3182921fc9 [DOI] [PubMed] [Google Scholar]
  • 110.Hernández-Aceituno A, Pérez-Tasigchana RF, Guallar-Castillón P, López-García E, Rodríguez-Artalejo F, Banegas JR. Combined healthy behaviors and healthcare services use in older adults. Am J Prev Med. 2017;53(6):872–81. doi: 10.1016/j.amepre.2017.06.023 [DOI] [PubMed] [Google Scholar]
  • 111.Christiansen J, Larsen FB, Lasgaard M. Do stress, health behavior, and sleep mediate the association between loneliness and adverse health conditions among older people?. Soc Sci Med. 2016;152:80–6. doi: 10.1016/j.socscimed.2016.01.020 [DOI] [PubMed] [Google Scholar]
  • 112.Arcaya MC, Tucker-Seeley RD, Kim R, Schnake-Mahl A, So M, Subramanian SV. Research on neighborhood effects on health in the United States: a systematic review of study characteristics. Soc Sci Med. 2016;168:16–29. doi: 10.1016/j.socscimed.2016.08.047 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 113.Sampson RJ. The place of context: a theory and strategy for criminology’s hard problems. Criminology. 2013;51(1):1–31. doi: 10.1111/1745-9125.12002 [DOI] [Google Scholar]
  • 114.Beard JR, Petitot C. Ageing and urbanization: can cities be designed to foster active ageing?. Public Health Rev. 2010;32(2):427–50. doi: 10.1007/bf03391610 [DOI] [Google Scholar]
  • 115.Schaefer-McDaniel N, Dunn JR, Minian N, Katz D. Rethinking measurement of neighborhood in the context of health research. Soc Sci Med. 2010;71(4):651–6. doi: 10.1016/j.socscimed.2010.03.060 [DOI] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

S1 Table. Variance Inflation Factor (VIF) and 1/VIF (tolerance) values of the selected variables.

(DOCX)

pgph.0005151.s001.docx (18.3KB, docx)

Data Availability Statement

The data used for this study is the Study on Global AGEing and Adult Health (SAGE) Wave 2 conducted by the World Health Organization. These data are publicly available on the National Archive of Computerized Data on Aging (NACDA) website https://www.icpsr.umich.edu/web/ICPSR/studies/31381/datadocumentation.


Articles from PLOS Global Public Health are provided here courtesy of PLOS

RESOURCES