Table 2.

The associations between fetal-exposed group and thyroid disorders with different control groups.

Fetal-exposed group No. of cases/sample size (%)	Control groups		OR [CI]	P
	Control groups	No. of cases/sample size (%)
Overt hyperthyroidism 5/373(1.3)	Non-exposed	3/986(0.3)	4.36(1.02–18.71)	0.048
	Childhood-exposed	6/597(1.0)	0.95(0.28–3.22)	0.931
	Age-balanced	8/1344(0.6)	2.13(0.68–6.64)	0.195
Subclinical hyperthyroidism 7/373(1.9)	Non-exposed	6/986(0.6)	3.13(1.03–9.51)	0.044
	Childhood-exposed	6/597(1.0)	1.77(0.58–5.43)	0.317
	Age-balanced	8/1344(0.6)	3.26(1.16–9.15)	0.025
Overt hypothyroidism 2/373(0.5)	Non-exposed	9/986(0.9)	0.51(0.11–2.39)	0.392
	Childhood-exposed	7/597(1.2)	0.44(0.09–2.24)	0.323
	Age-balanced	12/1344(0.9)	0.53(0.12–2.42)	0.414
Subclinical hypothyroidism 69/373(18.5)	Non-exposed	161/986(16.3)	1.09(0.79–1.49)	0.610
	Childhood-exposed	121/597(20.3)	0.92(0.66–1.30)	0.648
	Age-balanced	235/1344(17.5)	1.02(0.75–1.38)	0.905
TgAb positive 18/373(4.8)	Non-exposed	31/986(3.1)	1.40(0.77–2.56)	0.271
	Childhood-exposed	26/597(4.4)	1.03(0.55–1.93)	0.937
	Age-balanced	50/1344(3.7)	1.22(0.70–2.14)	0.483
TPOAb positive 43/373(11.5)	Non-exposed	96/986(9.7)	1.11(0.75–1.64)	0.597
	Childhood-exposed	64/597(10.7)	1.10(0.72–1.67)	0.674
	Age-balanced	135/1344(10.0)	1.10(0.76–1.59)	0.620
AIT 61/373(16.4)	Non-exposed	127/986(12.9)	1.21(0.86–1.70)	0.281
	Childhood-exposed	90/597(15.1)	1.09(0.75–1.57)	0.660
	Age-balanced	185/1344(13.8)	1.15(0.83–1.59)	0.403
Thyroid nodules 260/373(69.7)	Non-exposed	689/986(69.9)	0.97(0.74–1.26)	0.802
	Childhood-exposed	453/597(75.9)	0.69(0.51–0.93)	0.016*
	Age-balanced	959/1344(71.4)	0.89(0.69–1.15)	0.359

All the analysis adjusted for sex, smoking history, drinking history, dietary salt preference, current exercise status, education level, and BMI.

No., numbers; CI, confidence interval; OR, odds ratio.

^*FDR-adjusted p < 0.05.