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Summary of DEGs and enriched KEGG pathways.
| Group | KEGG | DEGs |
|---|---|---|
| HFHFD-Sema vs. HFHFD-NS and HFHFD-TZP vs. HFHFD-NS | Steroid hormone biosynthesis | Cyp1a1↑; Hsd11b1↑ |
| Metabolism of xenobiotics by cytochrome P450 | Cyp1a1↑; Hsd11b1↑ | |
| cAMP signaling pathway | Atp1a3↑ | |
| HFHFD-TZP vs. HFHFD-NS | TGF-beta signaling pathway | Tfrc↑ |
| Inflammatory mediator regulation of TRP channels | Il1b↓; Ptger4↓ |
