FIG. 5.

Infected cells develop multiple branched projections. BS-C-1 cells were seeded at low density to obtain isolated cells and then infected with VV at 5 PFU/cell. (A) Mock infection; (B) infection with VV; (C) infection with strain WR plus Ara-C; (D) infection with ΔB5R. Cells were photographed by phase-contrast microscopy at 24 hpi. (E) In different experiments (n = 4), between 100 and 120 cells were analyzed at 24 hpi and the proportion of cells showing three or more projections was calculated. Standard error bars are shown for each sample but are visible only for WR-infected cells.