Table II-1. Occupational exposure limits based on biological monitoring.
| Substance [CAS No.] | Assay material | Parameter | OEL-B | Sampling time | Year of proposal |
|---|---|---|---|---|---|
| Acetone [67-64-1] | urine | Acetonea | 40 mg/l | Within 2 h prior to end of shift | ʼ01 |
| 2-Butoxyethanol and 2-Butoxyethyl acetate [111-76-2, 112-07-2] |
urine | Butoxyacetic acida | 200 mg/g·Cr | End of shift | ʼ08 |
| Cadmium and compounds [7440-43-9] |
blood | Cadmiumb | 5 µg/l | Not critical | ’21 |
| urine | Cadmiumb | 5 µg/g·Cr | Not critical | ’21 | |
| Carbon disulfide [75-15-0] |
urine | 2-Thiothiazolidine-4-carboxylic acida | 0.5 mg/g·Cr | End of shift (Avoid sizable intake of brassica vegetables) | ʼ15 |
| Cobalt and inorganic compounds (Except cobalt oxides) [7440-48-4] |
blood | Cobalta | 3 μg/l | Within 2 h prior to end of shift at end of work week | ʼ05 |
| urine | Cobalta | 35 μg/l | Within 2 h prior to end of shift at end of work week | ʼ05 | |
| Chlorobenzene [108-90-7] |
urine | 4-Chlorocatechol (hydrolysis)a | 120 mg/g·Cr | End of shift | ʼ08 |
| 3,3’-Dichloro-4,4’-diaminodiphenylmethane (MBOCA, MOCA) [101-14-4] |
urine | total MOCAa | 10 μg/g·Cr | End of shift | ʼ23 |
| Dichloromethane [75-09-2] |
urine | Dichloromethanea | 0.2 mg/l | End of shift | ʼ05 |
| N,N-Dimethylacetamide [127-19-5] | urine | N-Methylacetamide | 25 mg/g·Cr† | End of shift at end of workweek |
ʼ25 |
| Ethylbenzene [100-41-4] |
urine | Mandelic acida | 150 mg/g·Cr | End of shift | ’21 |
| urine | Mandelic acid+ Phenylglyoxylic acida |
200 mg/g·Cr | End of shift at end of workweek | ’21 | |
| urine | Ethylbenzenea | 15 µg/l | End of shift | ’21 | |
| Hexane [110-54-3] | urine | 2,5-Hexanedionea | 3 mg/g·Cr (After acid hydrolysis) | End of shift at end of workweek | ʼ94 |
| urine | 2,5-Hexanedionea | 0.3 mg/g·Cr (Without acid hydrolysis) | End of shift at end of workweek | ʼ94 | |
| Indium and compounds [7440-74-6] |
serum | Indiumb | 3 μg/l | Not critical | ʼ07 |
| Lead and compounds (Except alkyl lead compounds) [7439-92-1] |
blood | Leadb | 15 μg/100 ml | Not critical | ʼ13 |
| blood | Protoporphyrin | 200 μg/100 ml·RBC | Not critical | ʼ94 | |
| 80 μg/100 ml·blood | (After one month or more since consecutive exposure) | ʼ94 | |||
| urine | δ-Aminolevulinic acid | 2 mg/g·Cr | Not critical | ʼ24 | |
| Mercury and compounds (Except alkyl mercury compounds) [7439-97-6] |
urine | total inorganic mercuryb | 35 μg/g·Cr | Not critical | ʼ93 |
| Methanol [67-56-1] | urine | Methanola | 20 mg/l | End of shift | ʼ10 |
| Methyl ethyl ketone [78-93-3] |
urine | Methyl ethyl ketonea | 5 mg/l | End of shift or a few hours after high exposure | ʼ06 |
| Methyl isobutyl ketone [108-10-1] | urine | Methyl isobytyl ketonea | 0.7 mg/l† | End of shift | ʼ25 |
| Phenol [108-95-2] | urine | Phenola | 250 mg/g·Cr | End of shift | ʼ08 |
| Polychlorinated biphenyls (PCBs) [53469-21-9, 11097-69-1, 1336-36-3] |
blood | total PCBsb | 25 μg/l | Not critical | ʼ06 |
| Styrene [100-42-5] | urine | Styrenea | 20 µg/l | End of shift at end of workweek | ’22 |
| urine | Mandelic acid + Phenylglyoxylic acida |
160 mg/g·Cr | End of shift at end of workweek | ’22 | |
| Tetrachloroethylene [127-18-4] |
blood | Tetrachloroethylene | 0.3 mg/l† | Prior to end of shift at end of workweek | ʼ25 |
| end-exhaled air | Tetrachloroethylene | 3 ppm† | Immediately after end of shift at end of workweek | ʼ25 | |
| urine | Tetrachloroethylene | 40 µg/l† | After end of shift at end of workweek | ʼ25 | |
| Tetrahydrofuran [109-99-9] |
urine | Tetrahydrofurana | 2 mg/l | End of shift | (ʼ15) |
| Toluene [108-88-3] | blood | Toluenea | 0.6 mg/l | Within 2 h prior to end of shift at end of work week | ʼ99 |
| urine | Toluenea | 0.06 mg/l | ʼ99 | ||
| Trichloroethylene [79-01-6] |
urine | Trichloroacetic acidb | 10 mg/l | End of shift at end of workweek | ’22 |
| blood | Trichloroethylene | Semi-quantitative | End of shift at end of workweek | ’22 | |
| end-exhaled air | Trichloroethylene | Semi-quantitative | End of shift at end of workweek | ’22 | |
| Xylene [95-47-6, 108-38-3, 106-42-3, 1330-20-7] | urine | total (o-, m-, p-) methylhippuric acida | 800 mg/l | End of shift at end of work week | ʼ05 |
1. In setting OEL-B, consideration is given to either:
a, The relationship between biological monitoring values and OEL-Ms.
b, The exposure-effect and/or exposure-response relationships between biological monitoring values and health effects.
2. †: Provisional
3. See the JSOH website for a brief summary of OEL documentation at https://www.sanei.or.jp/english/oels/index.html