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Diagramatic summary of intermonomer cross-links deduced from the BS3-cross-linking profiles of Lys-to-Arg mutants. Cross-links between two monomers are shown for clarity. N termini are closely juxtaposed, and Lys-678 is in close proximity to its intermonomer homologous residue. Lys-596 and/or Lys-612 of one monomer is in close proximity to lysine residues within both the N-terminal and C-terminal amphipathic α-helical sequences of an adjacent monomer(s). TM, transmembrane sequence.
