Table 2.
Mixed-effects linear regression model assessing HbA1c variation over time according to SES quartiles.
| Variable | Coefficient ( β ) | 95% confidence interval | p value |
|---|---|---|---|
| Time (post vs. pre) | −1.04 | –1.34 to –0.74 | < 0.001 |
| SES Quartile 2 | −0.82 | –1.52 to –0.13 | 0.020 |
| SES Quartile 3 | −0.59 | –1.29 to 0.12 | 0.102 |
| SES Quartile 4 | −1.02 | –1.73 to –0.30 | 0.005 |
| Interaction: time × Quartile 2 | 0.30 | –0.13 to 0.72 | 0.169 |
| Interaction: time × Quartile 3 | 0.20 | –0.23 to 0.62 | 0.361 |
| Interaction: time × Quartile 4 | 0.47 | 0.03 to 0.91 | 0.037 |
| Age | −0.012 | –0.023 to –0.001 | 0.034 |
| Sex (female) | 0.19 | –0.04 to 0.42 | 0.104 |
| Smoking | 0.42 | 0.12 to 0.73 | 0.007 |
| BMI | 0.007 | –0.019 to 0.032 | 0.607 |
| Other antidiabetics agents | 0.061 | –0.049 to 0.170 | 0.276 |
| Basal insulin (kg) | 0.39 | 0.03 to 0.75 | 0.033 |
Note: Results of the multivariable mixed-effects linear regression model evaluating changes in HbA1c before and after isCGM initiation, incorporating SES quartiles, time point (pre/post), and their interaction as fixed effects. The model is also adjusted for age, sex, smoking status, BMI, number of oral antidiabetic agents, and baseline insulin dose per kilogram. A random intercept at the patient level was included to account for repeated measures.
Abbreviations: BMI, body mass index; HbA1c; glycated hemoglobin; SES, socioeconomic status.