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. 2025 Sep 18;2025:6352081. doi: 10.1155/bca/6352081

Table 1.

Inhibition of cancer cell growth in three human cancer cell lines, determined by the MTT assay (exposure time: 96 h).

Compound A549 (μM) SW480 (μM) CH1 (μM)
Ru 3a
1a [5]
11 ± 1
24 ± 4
5.4 ± 1.1
9.5 ± 0.7
1.9 ± 0.1
3.0 ± 0.9
3b
1b [5]
20 ± 3
16 ± 1
7.9 ± 1.5
8.6 ± 0.9
2.8 ± 0.2
3.4 ± 0.2
3c
1c [5]
> 200
12 ± 1
> 200
5.1 ± 0.4
102 ± 11
1.6 ± 0.4
3d
1d [5]
7.2 ± 1.0
34 ± 3
3.8 ± 0.3
19 ± 2
1.61 ± 0.04
14 ± 2
3e
1e [5]
14 ± 1
27 ± 1
5.5 ± 2.2
17 ± 1
1.8 ± 0.3
7.3 ± 0.4

Os 4a
2a [5]
12 ± 1
17 ± 1
5.9 ± 1.9
9.3 ± 1.1
2.3 ± 0.2
3.0 ± 0.2
4b
2b [5]
20 ± 2
10 ± 1
7.4 ± 2.3
7.1 ± 0.3
2.7 ± 0.2
2.0 ± 0.4
4c
2c [5]
> 200
10 ± 1
> 200
4.4 ± 0.5
> 200
0.83 ± 0.14
4d
2d [5]
7.1 ± 0.6
17 ± 1
3.4 ± 0.9
9.3 ± 1.6
1.2 ± 0.2
3.7 ± 0.6
4e
2e [5]
24 ± 1
14 ± 1
8.1 ± 2.6
7.1 ± 1.2
2.1 ± 0.5
2.2 ± 0.3

Note: 50% inhibitory concentrations (means ± standard deviations) from at least three independent experiments.

IC50 values of the chlorido complexes were added as reference [5].