Table 3.
Generalized linear mixed-effect model analysis of the impact of work tasks (reference: baking and cooking) on log-transformed cytokine (pg/mL) of TNF-α, IL-6, IL-8, IL-10, IL-1β, IL-4, IL-2, and IL-12. Coefficients and P-values are presented for each predictor, with significant associations highlighted in bold. Random intercepts were included to account for variability between participants.
| Predictors | TNF-α | IL-1β | IL-8 | IL-2 | IL-6 | IL-4 | IL-10 | IL-12 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Estimates | P | Estimates | P | Estimates | P | Estimates | P | Estimates | P | Estimates | P | Estimates | P | Estimates | P | |
| Intercept | 3.117 | <0.001 | 2.995 | <0.001 | 5.920 | <0.001 | 1.487 | 0.004 | 0.779 | 0.011 | 3.358 | <0.001 | 0.607 | 0.192 | 2.904 | <0.001 |
| Work task (ref. “baking and cooking”) | ||||||||||||||||
| Cleaning | 0.155 | 0.888 | 0.122 | 0.928 | 0.189 | 0.862 | 0.911 | 0.457 | −0.103 | 0.884 | 0.347 | 0.694 | −0.201 | 0.859 | 0.083 | 0.931 |
| Delivery | 2.157 | 0.027 | 1.992 | 0.115 | 1.879 | 0.055 | 2.107 | 0.070 | 1.519 | 0.026 | 0.864 | 0.293 | 1.292 | 0.215 | 0.346 | 0.720 |
| Grinding and milling | −0.249 | 0.717 | −0.979 | 0.285 | −0.459 | 0.512 | −0.194 | 0.818 | −0.020 | 0.967 | −0.642 | 0.282 | −0.107 | 0.887 | −0.531 | 0.446 |
| Material handling | −0.607 | 0.203 | −0.845 | 0.173 | −0.815 | 0.090 | −0.135 | 0.812 | 0.001 | 0.997 | −0.203 | 0.614 | 0.833 | 0.104 | −0.383 | 0.415 |
| Packing | −2.314 | 0.002 | −1.907 | 0.052 | −2.042 | 0.007 | −0.785 | 0.381 | −0.737 | 0.161 | −1.089 | 0.088 | 0.358 | 0.657 | −0.394 | 0.598 |
| Production line operations | −1.479 | 0.001 | −1.956 | 0.001 | −1.850 | <0.001 | −0.540 | 0.326 | −0.296 | 0.358 | −0.642 | 0.100 | 0.334 | 0.499 | −0.366 | 0.424 |
| Storage | −0.876 | 0.267 | −0.728 | 0.467 | −1.312 | 0.097 | −0.557 | 0.543 | −0.451 | 0.398 | −0.657 | 0.315 | 0.735 | 0.377 | −0.318 | 0.671 |
| Weighing and mixing | 0.237 | 0.603 | 0.182 | 0.761 | 0.273 | 0.553 | 0.590 | 0.284 | 0.171 | 0.596 | 0.007 | 0.987 | −0.038 | 0.938 | −0.110 | 0.811 |
| Random effects | ||||||||||||||||
| σ2 | 0.97 | 2.10 | 1.06 | 1.82 | 0.66 | 0.87 | 1.36 | 1.48 | ||||||||
| τ00 identifier | 0.54 | 0.44 | 0.46 | 0.32 | 0.08 | 0.20 | 0.37 | 0.00 | ||||||||
| ICC | 0.36 | 0.17 | 0.30 | 0.15 | 0.10 | 0.19 | 0.21 | |||||||||
| N identifiers | 136 | 136 | 136 | 136 | 136 | 136 | 136 | 136 | ||||||||
| Observations | 194 | 194 | 194 | 194 | 194 | 194 | 194 | 194 | ||||||||
| Marginal R2/Conditional R2 | 0.299/0.549 | 0.261/0.388 | 0.367/0.560 | 0.118/0.248 | 0.096/0.186 | 0.094/0.265 | 0.067/0.266 | 0.016/NA | ||||||||