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. 2025 Jul 11;69(8):868–882. doi: 10.1093/annweh/wxaf041

Table 3.

Generalized linear mixed-effect model analysis of the impact of work tasks (reference: baking and cooking) on log-transformed cytokine (pg/mL) of TNF-α, IL-6, IL-8, IL-10, IL-1β, IL-4, IL-2, and IL-12. Coefficients and P-values are presented for each predictor, with significant associations highlighted in bold. Random intercepts were included to account for variability between participants.

Predictors TNF-α IL-1β IL-8 IL-2 IL-6 IL-4 IL-10 IL-12
Estimates P Estimates P Estimates P Estimates P Estimates P Estimates P Estimates P Estimates P
Intercept 3.117 <0.001 2.995 <0.001 5.920 <0.001 1.487 0.004 0.779 0.011 3.358 <0.001 0.607 0.192 2.904 <0.001
Work task (ref. “baking and cooking”)
 Cleaning 0.155 0.888 0.122 0.928 0.189 0.862 0.911 0.457 −0.103 0.884 0.347 0.694 −0.201 0.859 0.083 0.931
 Delivery 2.157 0.027 1.992 0.115 1.879 0.055 2.107 0.070 1.519 0.026 0.864 0.293 1.292 0.215 0.346 0.720
 Grinding and milling −0.249 0.717 −0.979 0.285 −0.459 0.512 −0.194 0.818 −0.020 0.967 −0.642 0.282 −0.107 0.887 −0.531 0.446
 Material handling −0.607 0.203 −0.845 0.173 −0.815 0.090 −0.135 0.812 0.001 0.997 −0.203 0.614 0.833 0.104 −0.383 0.415
 Packing −2.314 0.002 −1.907 0.052 −2.042 0.007 −0.785 0.381 −0.737 0.161 −1.089 0.088 0.358 0.657 −0.394 0.598
 Production line operations −1.479 0.001 −1.956 0.001 −1.850 <0.001 −0.540 0.326 −0.296 0.358 −0.642 0.100 0.334 0.499 −0.366 0.424
 Storage −0.876 0.267 −0.728 0.467 −1.312 0.097 −0.557 0.543 −0.451 0.398 −0.657 0.315 0.735 0.377 −0.318 0.671
 Weighing and mixing 0.237 0.603 0.182 0.761 0.273 0.553 0.590 0.284 0.171 0.596 0.007 0.987 −0.038 0.938 −0.110 0.811
Random effects
 σ2 0.97 2.10 1.06 1.82 0.66 0.87 1.36 1.48
 τ00 identifier 0.54 0.44 0.46 0.32 0.08 0.20 0.37 0.00
 ICC 0.36 0.17 0.30 0.15 0.10 0.19 0.21
N identifiers 136 136 136 136 136 136 136 136
 Observations 194 194 194 194 194 194 194 194
 Marginal R2/Conditional R2 0.299/0.549 0.261/0.388 0.367/0.560 0.118/0.248 0.096/0.186 0.094/0.265 0.067/0.266 0.016/NA