TABLE 2.
The cost and outcome results of the base-case analysis.
| Parameters | Overall population | PD–L1 CPS ⩾5 population | ||||||
|---|---|---|---|---|---|---|---|---|
| Chinese perspective | United States perspective | Chinese perspective | United States perspective | |||||
| Switch maintenance group | Control group | Switch maintenance group | Control group | Switch maintenance group | Control group | Switch maintenance group | Control group | |
| Total cost ($) | 69,852.42 | 13,114.09 | 256,611.11 | 713,60.56 | 75,556.47 | 12,815.23 | 276,370.43 | 70,263.30 |
| Incremental costs ($) | 56,738.52 | – | 185,250.55 | – | 62,741.24 | – | 206,107.13 | – |
| Overall QALYs | 0.89 | 0.74 | 0.91 | 0.76 | 1.02 | 0.79 | 1.05 | 0.80 |
| Incremental QALYs | 0.15 | – | 0.16 | – | 0.24 | – | 0.25 | – |
| ICER ($/QALY) | 373,219.84 | 1,193,220.74 | 266,259.94 | 835,740.90 | ||||
Abbreviations: CPS, combined positive score; ICER, incremental cost-effectiveness ratio; QALYs, quality-adjusted life-years.
The bold font represents the ratio of incremental costs to incremental QALYs between the two treatment groups.