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. 2025 Sep 12;16:1615380. doi: 10.3389/fendo.2025.1615380

Table 1.

Baseline characteristics of the study participants.

Baseline Characteristics Q1 (n=390) Q2 (n=390) Q3 (n=390) Q4 (n=390) χ²/F/H P ##
Age (years)* 63.63 ± 11.11 61.21 ± 10.50 57.96 ± 11.53 54.88 ± 11.99 44.507 <0.001a
Male** 257 (65.90) 252 (64.62) 253 (64.87) 266 (68.21) 1.392 0.707
Current Smoking** 79 (20.26) 85 (21.79) 83 (21.28) 105 (26.92) 5.929 0.115
Current Drinking** 78 (20.00) 76 (19.49) 90 (23.08) 105 (26.92) 7.895 0.048
DBP (mmHg)* 71.46 ± 9.98 72.33 ± 9.65 72.53 ± 10.22 73.22 ± 11.25 1.774 0.15
SBP (mmHg)* 126.83 ± 12.99 127.02 ± 12.90 126.73 ± 12.26 126.98 ± 13.57 0.041 0.989
BMI (kg/m²)# 23.5 (21.6,25.6) 24.6 (22.3,26.6) 25.4 (23.4,27.5) 26.5 (23.8,28.9) 145.637 <0.001a
TG (mmol/L)# 0.94 (0.76,1.11) 1.41 (1.19,1.66) 1.98 (1.68,2.41) 3.67 (2.62,5.46) 1122.488 <0.001a
TC (mmol/L)# 4.32 (3.58,4.96) 4.60 (3.84,5.27) 4.9 (4.23,5.61) 5.24 (4.48,6.03) 145.868 <0.001a
HDL-C (mmol/L)# 1.39 (1.16,1.67) 1.29 (1.08,1.54) 1.21 (1.03,1.45) 1.07 (0.87,1.23) 221.978 <0.001b
LDL-C (mmol/L)* 2.36 ± 0.82 2.64 ± 0.81 2.80 ± 0.80 2.81 ± 0.90 24.348 <0.001c
FPG (mmol/L)# 6.30 (5.35,7.26) 7.67 (6.61,8.86) 8.71 (7.45,10.44) 11.22 (8.72,15.11) 610.387 <0.001a
MS** 23 (5.89) 72 (18.26) 175 (44.87) 239 (61.28) 334.638 <0.001d
Overweight or Obesity** 122 (31.28) 182 (46.47) 213 (54.62) 250 (64.10) 90.33 <0.001e
Hypertension** 109 (27.95) 107 (27.44) 100 (25.64) 113 (28.97) 1.141 0.767
Dyslipidemia** 79 (20.26) 79 (20.26) 97 (24.87) 131 (33.60) 24.827 <0.001f

*Data are presented as mean ± standard deviation; **Data in parentheses are rates (%), and data outside parentheses are counts; #Data outside parentheses are medians, and data inside parentheses are P25 and P75.

##Adjusted for multiple testing correction using the Bonferroni method.

aPairwise comparisons among all four groups showed statistically significant differences, P < 0.05;

bNo significant difference was observed between the Q2 and Q3 groups, while significant differences existed in all other pairwise comparisons, P < 0.05;

cNo significant difference was found between the third and fourth groups, whereas all other pairwise comparisons showed significant differences, P < 0.05;

dNo statistically significant differences in MS rates were observed among the groups;

eSignificant differences existed between Q2 and the other three groups, P < 0.05, with no differences among the remaining groups;

fSignificant differences existed between Q4 and the other three groups, P < 0.05, with no differences among the remaining groups.