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. 1998 Feb;72(2):1552–1576. doi: 10.1128/jvi.72.2.1552-1576.1998

TABLE 4.

Antigen-specific antibodies and total immunoglobulins in mucosal secretions

Volunteer Immunogen Visit no. Specimen Concn of antigen-specific immunoglobulin (ng/ml)
Total immunoglobulin concn (ng/ml)
IgA IgG IgA IgG
C05 SF-2 6 mo Vaginal wash 0 243 0 129,680
6 mo Cervical wick 0 436 0 688
8 Cervical wick 0 2,597  NDa ND
C09 SF-2 2 Parotid saliva 33 0 79,644 1,486
2 Semen 0 109 37,498 64,780
C10 MN 2 Seminal plasma 36 207 17,403 35,247
3 Parotid saliva 239 18 800,100 5,346
5 Parotid saliva 180 43 482,220 10,262
6 Parotid saliva 113 35 264,090 4,280
6 Parotid saliva 154 24 360,650 3,658
C12 Placebo 2 Parotid saliva 27 0 117,760 856
4 Parotid saliva 23 0 114,700 838
5 Parotid saliva 19 0 85,011 1,442
6 Parotid saliva 18 0 60,247 2,779
8 Parotid saliva 19 0 215,407 856
pC12 1 Parotid saliva 60 0 491,530 3,122
1 Semen 0 223 41,632 58,012
C16 SF-2 2 Parotid saliva 22 0 133,450 1,983
2 Pre-ejaculate 0 0 1,244 735
2 Rectal wick 68 10 589,450 30,275
2 Seminal plasma 27 18 134,130 113,710
5 Nasal wash 28 10 86,715 9,021
5 Parotid saliva 22 0 238,120 1,871
6 Parotid saliva 15 0 197,370 6,202
6 Pre-ejaculate 0 0 ND ND
6 Rectal wick 0 0 ND ND
8 Parotid saliva 0 0 ND ND
pC16 1 Parotid saliva 10 11 54,465 979
1 Pre-ejaculate 0 0 24 11
1 Rectal wick 0 21 7,975 1,652
8 Parotid saliva 21 0 166,321 227
C17 MN 2 Parotid saliva 61 5 240,400 3,133
5 Parotid saliva 45 8 155,370 2,084
6 Parotid saliva 23 13 206,800 2,368
8 Parotid saliva 29 12 235,876 2,532
C18 Placebo 2 Parotid saliva 0 0 161,160 4,089
2 Seminal plasma 0 13 35,288 100,690
5 Parotid saliva 33 0 189,890 1,301
6 Parotid saliva 29 0 393,177 778
8 Parotid saliva 26 2 365,619 808
C20 SF-2 5 Parotid saliva 44 3 588,480 12,621
6 Parotid saliva 28 0 399,988 901
C21 SF-2 1 Parotid saliva 27 3 115,010 1,190
5 Parotid saliva 26 4 486,308 1,997
6 Parotid saliva 27 10 882,237 3,589
8 Parotid saliva 0 41 ND ND
C24 MN 2 Parotid saliva 38 13 171,498 3,370
5 Parotid saliva 50 25 213,037 5,714
C25 MN 2 Parotid saliva 39 17 1,370,000 18,332
5 Parotid saliva 20 0 252,208 2,081
a

ND, not determined.