Table 3.

Differentially expressed mRNA enrichment pathway rich factors and P-values.

Pathway name	Rich_factor	P-value	Model vs. Normal/AS vs. Model
Taurine and hypotaurine metabolism	5.657760	0.00438948	M vs. N
Primary bile acid biosynthesis	4.125450	0.00323554	M vs. N
Vitamin B6 metabolism	3.960432	0.01528459	M vs. N
Biosynthesis of unsaturated fatty acids	3.850420	0.00124750	M vs. N
Ascorbate and aldarate metabolism	3.696403	0.00161791	M vs. N
Steroid biosynthesis	3.474063	0.00749106	M vs. N
alpha-Linolenic acid metabolism	3.143200	0.01202614	M vs. N
Nicotinate and nicotinamide metabolism	2.980970	0.00607574	M vs. N
Phenylalanine metabolism	2.514560	0.04703768	M vs. N
Metabolism of xenobiotics by cytochrome P450	2.329666	0.00554278	M vs. N
Cholesterol metabolism	2.329666	0.01349901	M vs. N
Linoleic acid metabolism	2.200240	0.04409226	M vs. N
Arginine and proline metabolism	2.200240	0.02558563	M vs. N
Ether lipid metabolism	2.149071	0.03795379	M vs. N
Arachidonic acid metabolism	2.140774	0.01100428	M vs. N
Retinol metabolism	1.885920	0.03463675	M vs. N
Steroid hormone biosynthesis	1.838175	0.04116785	M vs. N
PPAR signaling pathway	4.863504	0.00002685	AS vs. M
One carbon pool by folate	4.405762	0.02281231	AS vs. M
Steroid biosynthesis	3.941998	0.03060684	AS vs. M
Aldosterone-regulated sodium reabsorption	3.120748	0.03454257	AS vs. M
Aldosterone synthesis and secretion	2.880691	0.00791804	AS vs. M
Adipocytokine signaling pathway	2.674927	0.02603838	AS vs. M
cAMP signaling pathway	2.226696	0.01157477	AS vs. M
AMPK signaling pathway	2.221550	0.03351424	AS vs. M