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. 2025 Sep 26;25:113. doi: 10.1186/s40644-025-00930-9

Table 3.

Quantitative measurements and inter-reader ICC comparison between conventional and SMS sequences

Parameters Quantitative measurement P ICC (95%CI) for 3 readers
CON SMS P CON SMS
ADC ‡ 1.17 ± 0.23 1.13 ± 0.19 < 0.001 ** 0.879 (0.873–0.882) 0.877 (0.871–0.891)
D † 1.02 ± 0.15 1.01 ± 0.15 0.555 0.817 (0.792–0.832) 0.836 (0.803–0.854)
D* ‡ 24.69 ± 6.02 24.93 ± 5.93 0.231 0.804 (0.779–0.837) 0.811 (0.782–0.843)
f ‡ 30.23 ± 4.46 27.06 ± 3.99 0.003 ** 0.719 (0.615–0.794) 0.702 (0.641–0.778)
MK † 0.81 ± 0.14 0.82 ± 0.13 0.123 0.822 (0.802–0.851) 0.821 (0.793–0.847)
MD ‡ 1.62 ± 0.24 1.62 ± 0.25 0.767 0.815 (0.789–0.843) 0.823 (0.805–0.855)

ADC, D, MD, and D* are measured in × 10⁻³ mm²/s

f represents the perfusion fraction expressed as a percentage

†, Paired t test; ‡, Wilcoxon signed-rank test; *, P-value < 0.05; **, P-value < 0.01

CON, conventional; SMS, simultaneous multislice; ICC, intraclass correlation coefficient; CI, confidence interval; ADC, apparent diffusion coefficient; D, true diffusion coefficient; D*, perfusion-related diffusion; f, perfusion fraction; MK, mean kurtosis; MD, mean diffusivity