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. 2025 Sep 26;30:866. doi: 10.1186/s40001-025-03134-w

Table 1.

Diagnostic criteria of acute cholecystitis by the Tokyo guidelines 2013/2018

A. Local signs of inflammation etc.:

1. Murphy’s sign

2. Mass/pain/tenderness over the right upper quadrant (RUQ) of the abdomen

B. Systemic signs of inflammation etc.:

1. Elevated white blood cell (WBC) count

2. Elevated C-reactive protein (CRP)

3. Fever

C. Imaging findings
Suspected diagnosis: one item in A + one item in B
Definite diagnosis: one item in A + one item in B + C