Table 2.
HRs of muscle, adipose and bone parameters per SD decrease for FNF death risk
| Unadjusted | Adjusteda | Adjustedb | Adjustedc | |||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| G.MaxM area (cm2) | 0.91(0.85,0.97) | < 0.01 | 0.93(0.86,1.01) | 0.07 | 0.93(0.87,1.01) | 0.08 | 0.93(0.86,1.00) | 0.06 |
| G.MaxM density (HU) | 0.92(0.87,0.97) | < 0.01 | 0.97(0.90,1.04) | 0.34 | 0.96(0.90,1.03) | 0.27 | 0.96(0.90,1.03) | 0.27 |
| G.Med/MinM area (cm2) | 0.86(0.79,0.93) | < 0.01 | 0.88(0.80,0.96) | < 0.01 | 0.88(0.81,0.96) | < 0.01 | 0.88(0.81,0.96) | < 0.01 |
| G.Med/MinM density (HU) | 0.86(0.80,0.92) | < 0.01 | 0.90(0.82,0.98) | 0.01 | 0.89(0.82,0.97) | 0.01 | 0.89(0.82,0.97) | 0.01 |
| MM area (cm2) | 0.97(0.94,1.00) | 0.02 | 0.99(0.95,1.03) | 0.52 | 0.99(0.95,1.02) | 0.42 | 0.99(0.95,1.02) | 0.47 |
| MM density (HU) | 0.87(0.81,0.93) | < 0.01 | 0.91(0.84,1.00) | 0.04 | 0.91(0.84,0.99) | 0.03 | 0.91(0.84,0.99) | 0.03 |
| MSAT area (cm2) | 0.99(0.97,1.01) | 0.15 | 0.99(0.97,1.01) | 0.36 | 0.99(0.97,1.01) | 0.30 | 0.99(0.97,1.01) | 0.29 |
| MSAT density (HU) | 0.97(0.89,1.06) | 0.50 | 0.96(0.88,1.04) | 0.32 | 0.96(0.89,1.04) | 0.34 | 0.96(0.88,1.05) | 0.35 |
| TH aBMD (mg/cm2) | 1.00(0.99,1.000) | 0.08 | 1.00(1.00,1.00) | 0.85 | 1.00(1.00,1.00) | 0.81 | 1.00(1.00,1.00) | 0.73 |
| FN aBMD (mg/cm2) | 1.00(0.99,1000) | 0.06 | 1.00(0.99,1.00) | 0.64 | 1.00(0.99,1.00) | 0.68 | 1.00(0.99,1.00) | 0.52 |
| TR aBMD (mg/cm2) | 1.00(0.99,1.00) | 0.14 | 1.00(1.00,1.01) | 0.88 | 1.00(1.00,1.01) | 0.98 | 1.000(1.00,1.01) | 0.97 |
| IT aBMD (mg/cm2) | 1.00(0.99,1.00) | 0.07 | 1.00(1.00,1.00) | 0.77 | 1.00(1.00,1.00) | 0.75 | 1.00(1.00, 1.00) | 0.66 |
| Parker Mobility Score 1 | 0.83(0.69,0.99) | 0.04 | NA | NA | NA | NA | NA | NA |
| Parker Mobility Score 2 | 0.82(0.73,0.92) | < 0.01 | NA | NA | NA | NA | NA | NA |
| ASA score | 2.50(1.20,5.20) | 0.02 | NA | NA | NA | NA | NA | NA |
| CCI | 2.90(1.84,4.57) | < 0.01 | NA | NA | NA | NA | NA | NA |
* FNF, femoral neck fracture; aBMD, areal bone mineral density; ASA, American Society of Anesthesiologists; CCI, Charlson Comorbidity Index; HR, hazard ratio; SD, standard deviance; CI, confidence interval; G.MaxM, gluteus maximus muscle; G.Med/MinM, gluteus medius and minimus muscle; MM, midthigh muscle; MSAT, mid-thigh subcutaneous adipose tissue; TH, total hip; FN, femoral neck; TR, trochanter; IT, intertrochanter
Note: Parker Mobility Score 1: assessment obtained prior to hip fracture surgery; Parker Mobility Score 2: assessment within 3 months prior to death; Group without death: assessment of mobility prior to follow-up visit
aAdjusted for age, BMI, and ASA score
bAdjusted for age, BMI, and CCI
cAdjusted for age, BMI, and Parker Mobility Score prior to hip fracture surgery