Table 3.
HRs of muscle, adipose and bone parameters per SD decrease for ITF death risk
| Unadjusted | Adjusteda | Adjustedb | Adjustedc | |||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| G.MaxM area (cm2) | 0.91(0.86,0.97) | < 0.01 | 0.96(0.90,1.03) | 0.28 | 0.96(0.90,1.03) | 0.29 | 0.96(0.89,1.03) | 0.22 |
| G.MaxM density (HU) | 0.97(0.93,1.01) | 0.09 | 1.00(0.96,1.05) | 0.98 | 1.00(0.96,1.05) | 0.95 | 1.00(0.96,1.05) | 1.00 |
| G.Med/MinM area (cm2) | 0.93(0.88,0.99) | 0.03 | 0.99(0.93,1.06) | 0.77 | 0.99(0.93,1.06) | 0.77 | 0.99(0.93,1.06) | 0.76 |
| G.Med/MinM density (HU) | 0.97(0.93,1.01) | 0.15 | 1.03(0.97,1.09) | 0.36 | 1.03(0.97,1.09) | 0.36 | 1.02(0.97,1.08) | 0.41 |
| MM area (cm2) | 0.96(0.94,0.99) | < 0.01 | 0.99(0.96,1.01) | 0.31 | 0.99(0.96,1.01) | 0.31 | 0.98(0.96,1.01) | 0.25 |
| MM density (HU) | 0.96(0.91,1.01) | 0.11 | 1.01(0.95,1.08) | 0.69 | 1.02(0.95,1.08) | 0.63 | 1.01(0.95,1.08) | 0.68 |
| MSAT area (cm2) | 0.98(0.96,0.99) | < 0.01 | 0.98(0.96,1.00) | 0.01 | 0.98(0.96,1.00) | 0.01 | 0.98(0.96,1.00) | 0.01 |
| MSAT density (HU) | 1.06(1.02,1.11) | < 0.01 | 1.05(1.01,1.09) | 0.02 | 1.05(1.01,1.09) | 0.02 | 1.05(1.01,1.09) | 0.02 |
| TH aBMD (mg/cm2) | 0.99(0.99,1.00) | < 0.01 | 1.00(0.99,1000) | 0.04 | 1.00(0.99,1.00) | 0.04 | 1.00(0.99,1.00) | 0.03 |
| FN aBMD (mg/cm2) | 0.99(0.99,1.00) | < 0.01 | 1.00(0.99,1.00) | 0.42 | 1.00(0.99,1.00) | 0.37 | 1.00(0.99,1.00) | 0.30 |
| TR aBMD (mg/cm2) | 0.99(0.99,1.00) | < 0.01 | 1.00(0.99,1.000) | 0.05 | 1.00(0.99,1.00) | 0.04 | 1.00(0.99,1.00) | 0.03 |
| IT aBMD (mg/cm2) | 1.00(0.99,1.00) | < 0.01 | 1.00(0.99,1.000) | 0.06 | 1.00(0.99,1.00) | 0.05 | 1.00(0.99,1.00) | 0.04 |
| Parker Mobility Score 1 | 0.96(0.83,1.11) | 0.59 | NA | NA | NA | NA | NA | NA |
| Parker Mobility Score 2 | 0.81(0.72,0.90) | < 0.01 | NA | NA | NA | NA | NA | NA |
| ASA score | 1.94(0.99,3.78) | 0.05 | NA | NA | NA | NA | NA | NA |
| CCI | 2.59(1.22,5.47) | 0.01 | NA | NA | NA | NA | NA | NA |
* ITF, intertrochanteric fracture; aBMD, areal bone mineral density; ASA, American Society of Anesthesiologists; CCI, Charlson Comorbidity Index; HR, hazard ratio; SD, standard deviance; CI, confidence interval; G.MaxM, gluteus maximus muscle; G.Med/MinM, gluteus medius and minimus muscle; MM, midthigh muscle; MSAT, mid-thigh subcutaneous adipose tissue; TH, total hip; FN, femoral neck; TR, trochanter; IT, intertrochanter
Note: Parker Mobility Score 1: assessment obtained prior to hip fracture surgery; Parker Mobility Score 2: assessment within 3 months prior to death; Group without death: assessment of mobility prior to follow-up visit
aAdjusted for age, BMI, and ASA score
bAdjusted for age, BMI, and CCI
cAdjusted for age, BMI, and Parker Mobility Score prior to hip fracture surgery