Table 3.
Factors Contributing to Coronary Artery Disease: Stepwise Logistic Regression Analysis
| Variable | B | SE | p | OR | 95% CI for OR | |
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| All ( n =723) | ||||||
| Age (year) | 0.04 | 0.02 | .008 ** | 1.04 | 1.01 | 1.08 |
| Sex (male) | 1.13 | 0.37 | .002 ** | 3.09 | 1.49 | 6.42 |
| Diabetes history (yes) | 0.84 | 0.36 | .021* | 2.32 | 1.14 | 4.72 |
| Psychological disease history (yes) | −2.45 | 1.29 | .058 | 0.09 | 0.01 | 1.09 |
| Current smoker (yes) | 1.21 | 0.38 | .001 ** | 3.37 | 1.60 | 7.09 |
| Low-density lipoprotein (mg/dL) | 0.01 | 0.00 | .002 ** | 1.01 | 1.01 | 1.02 |
| eGFR (mL/min/1.73 m2) | −0.02 | 0.01 | .009 ** | 0.98 | 0.97 | 1.00 |
| Typical angina | 0.68 | 0.30 | .025* | 1.97 | 1.09 | 3.54 |
| Age <65 (n=454) | ||||||
| Age (year) | 0.07 | 0.02 | <.001 ** | 1.07 | 1.03 | 1.12 |
| Sex (male) | 0.97 | 0.42 | .021* | 2.63 | 1.16 | 5.97 |
| Current smoker (yes) | 1.05 | 0.34 | .002 ** | 2.86 | 1.48 | 5.56 |
| Low-density lipoprotein (mg/dL) | 0.01 | 0.00 | .025* | 1.01 | 1.00 | 1.02 |
| Uric acid (mg/dL) | 0.20 | 0.10 | .045* | 1.22 | 1.00 | 1.49 |
| High-sensitivity CRP (mg/L) | 0.08 | 0.04 | .036* | 1.08 | 1.01 | 1.17 |
| Typical angina | 0.80 | 0.30 | .008 ** | 2.22 | 1.23 | 3.99 |
| Age ≥65 (n=269) | ||||||
| Diabetes history (yes) | 1.95 | 0.59 | .001 ** | 7.00 | 2.19 | 22.34 |
| Psychological disease history (yes) | −2.06 | 1.02 | .043* | 0.13 | 0.02 | 0.94 |
| Angina frequency (ref=none) | ||||||
| 1–3 times/month | 2.46 | 0.77 | .001 ** | 11.74 | 2.59 | 53.14 |
| 1–2 times/week | 1.66 | 0.64 | .010* | 5.25 | 1.49 | 18.47 |
| 3–6 times/week | 0.94 | 0.82 | .248 | 2.57 | 0.52 | 12.76 |
| ≥7 times/week | 1.44 | 1.27 | .255 | 4.24 | 0.35 | 50.96 |
| Females (n = 118) | ||||||
| Diabetes history (yes) | 2.27 | 0.63 | <.001 ** | 9.70 | 2.84 | 33.15 |
| Males (n = 605) | ||||||
| Age (year) | 0.05 | 0.01 | <.001 ** | 1.05 | 1.02 | 1.08 |
| Diabetes history (yes) | 0.76 | 0.34 | .028* | 2.13 | 1.09 | 4.17 |
| Psychological disease history (yes) | −1.95 | 0.94 | .038* | 0.14 | 0.02 | 0.89 |
| High-density lipoprotein (mg/dL) | −0.03 | 0.01 | .040* | 0.97 | 0.94 | 1.00 |
| Low-density lipoprotein (mg/dL) | 0.02 | 0.00 | <.001 ** | 1.02 | 1.01 | 1.03 |
| High-sensitivity CRP (mg/L) | 0.07 | 0.04 | .053 | 1.07 | 1.00 | 1.15 |
| Typical angina | 0.60 | 0.27 | .024* | 1.83 | 1.08 | 3.09 |
Note. The overall accuracy of the prediction model was 78.5%. In the subgroups, accuracy rates were 74.2% for age <65, 86.2% for age ≥65, 71.4% for females, and 78.9% for males. eGFR = estimated Glomerular Filtration Rate; CRP = C-reactive protein.
*
p < .05. **p < .01.