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. 2025 Sep 22;14(9):957. doi: 10.3390/antibiotics14090957
HAP Hospital-acquired pneumonia
VAP Ventilator-associated pneumonia
ELF Pulmonary Epithelial lining fluid
PK Pharmacokinetic
PK/PD pharmacokinetic/pharmacodynamic
BALF Bronchoalveolar lavage fluid
ICU Intensive care units
MDR Multidrug-resistant
CRAB Carbapenem-resistant Acinetobacter baumannii
CRKP Carbapenem-resistant Klebsiella pneumoniae
XDR Extensively drug-resistant
CRE Carbapenem-resistant Enterobacteriaceae
cIAI Complicated intra-abdominal infections
TFA Trifluoroacetic acid
MRM Multiple reaction monitoring
NS Normal saline
LLOQ Lower limit of quantification
MF Matrix factor
DF Dilution factor
ESI Electrospray ionization
BAL Bronchoalveolar lavage
TDM therapeutic drug monitoring
fAUC/MIC free area under the concentration–time curve to the minimum inhibitory concentration
PTA probability of target attainment
PPK population pharmacokinetic