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. 2025 Aug 22;14(9):1031. doi: 10.3390/antiox14091031
PD Parkinson’s disease
MnP Manganese porphyrin
MnBuOE MnTnBuOE-2-PyP5+, manganese(III) meso-tetrakis(N-butoxyethylpyridinium-2-yl)porphyrin, BMX-001
MnE MnTE-2-PyP5+, manganese(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, BMX-010, AEOL10113
roGFP2 redox-sensitive green fluorescent protein
ROS reactive oxygen species
SOD superoxide dismutase
NF-κB nuclear factor-kappa B
Nrf2 NF-E2-related factor 2
Keap1 kelch-like-ECH-associated protein 1
GRE glutathione redox equilibrium
GSH reduced glutathione
PPL1 protocerebral posterior lateral 1
Orp1 oxidant receptor peroxidase 1
Grx1 glutaredoxin 1
TH tyrosine hydroxylase
UAS upstream activating sequence
park+/+ control Drosophila park genotype
park−/− homozygous park loss-of-function genotype
NEM N-ethylmaleimide
PBT phosphate buffer with Triton X-100
LC-MS/MS liquid chromatography tandem mass spectrometry
SEM standard error of the mean