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. 2025 Sep 9;13(9):2208. doi: 10.3390/biomedicines13092208
WHO World Health Organization
T2D Type 2 Diabetes
CVD Cardiovascular Diseases
MASLD Metabolic-associated Steatotic Liver Disease
WAT White adipose tissue
AT Adipose Tissue
PWO People With Obesity
ILC2s Group 2 Innate Lymphoid Cells
IL Interleukin
IFN-γ Interferon-gamma
TNF-α Tumor Necrosis Factor alpha
BMI Body Mass Index
GATA3 GATA Binding Protein 3
IgG1/IgE Immunoglobulin G1/E
HDL-C High-Density Lipoprotein Cholesterol
SAT Subcutaneous Adipose Tissue
BAT Brown Adipose Tissue
VAT Visceral Adipose Tissue
MCP-1 Monocyte Chemoattractant Protein-1
HGF Hepatocyte Growth Factor
NFκB Nuclear Factor Kappa-light-chain-enhancer of Activated B Cells
IK-Kβ IκB Kinase beta
JNK c-Jun N-terminal Kinase
NLRP3 NOD-, LRR- and pyrin domain-containing protein 3
IR Insulin Resistance
EAT Epicardial Adipose Tissue
PVAT Perivascular Adipose Tissue
LDL Low -Density Lipoprotein
HDL High -dDensity Lipoprotein
LPS Lipopolysaccharides
TLR Toll-like receptor
DCs Dendritic Cells
CD Cluster of Differentiation (e.g., CD4, CD8, CD25)
CLS Crown-like Structures
CCL2 C-C Motif Chemokine Ligand 2
LTB4 Leukotriene B4
SV Stromal Vascular
PRRs Pattern Recognition Receptors
CCR C-C Chemokine Receptor
MMEs Metabolic- Activated Macrophages
ABCA1 ATP-Bbinding Cassette Transporter
TPH-1 Tryptophan Hydrolase 1
UCP-1 Uncoupling Protein 1
HFD High Fat Diet
NETs Neutrophil Extracellular Traps
CRAMP Cathelicidin-Related Antimicrobial Peptide
DIO Diet-Induced Obesity
SpDCs Splenic Dendritic Cells
FAO Fatty Acid Oxidation
Ag Antigen
Tc1 Type 1 Cytotoxic T cells
PD-1 Programmed cell death 1
TCR T Cell Receptor
Teff2 T-effector CD4+ cells
APCs Antigen Presenting Cells
IL-4Rα Interleukin 4 Receptor alpha
FA/FAs Fatty Acid(s)
STAT Signal Transducer and Activator of Transcription
PPARα Peroxisome Proliferator-Activated Receptor alpha
Fgf21 Fibroblast Growth Factor 21
AKT Protein Kinase B
HSL Hormone- Sensitive Lipase
cAMP Cycle adenosine monophosphate
PKA Protein Kinase A
Tregs Regulatory T Cells
Th1/Th2/Th17 T helper 1/2/17 cells
AT-EOS Adipose Tissue Eosinophils
TGF-β Transforming Growth Factor beta
MIP-1α Macrophage Inflammatory Protein-1 alpha
AAMs Alternative Activated Macrophages
ERK Extracellular signal-regulated kinase
ERR Estrogen- Related Receptor
GDFIS Growth Differentiation Factor 15
GFRAL GDNF Family Receptor alpha-like