AAV |
Adeno-associated virus |
AFP |
Alpha-fetoprotein |
AKT |
Protein kinase B |
ASO |
Antisense oligonucleotide |
AUC |
Area under the curve |
CAM |
Chorio-allantoic membrane |
CAF |
Cancer-associated fibroblast |
CH |
Chronic hepatitis |
CHB |
Chronic hepatitis B |
DEN |
Diethylnitrosamine |
DFS |
Disease-free survival |
DNMT1 |
DNA methyltransferase 1 (gene symbol) |
DNA |
Deoxyribonucleic acid |
EGFR |
Epidermal growth factor receptor |
EMT |
Epithelial–mesenchymal transition |
EV |
Extracellular vesicle |
FDG-PET |
Fluorodeoxyglucose positron emission tomography |
FASN |
Fatty acid synthase (gene symbol) |
GEMM |
Genetically engineered mouse model |
G6PD |
Glucose-6-phosphate dehydrogenase |
G6PC |
Glucose-6-phosphatase |
HDAC |
Histone deacetylase |
HCC |
Hepatocellular carcinoma |
HBV |
Hepatitis B virus |
HCV |
Hepatitis C virus |
HK2 |
Hexokinase 2 (gene symbol) |
HIF-1α |
Hypoxia-inducible factor 1 alpha |
IL-6 |
Interleukin-6 |
LDHA |
Lactate dehydrogenase A |
LNA |
Locked nucleic acid |
LNP |
Lipid nanoparticle |
LP |
Liposome (carrier) |
miRNA |
MicroRNA |
mTOR |
Mechanistic target of rapamycin |
NAFLD |
Non-alcoholic fatty liver disease |
NASH |
Non-alcoholic steatohepatitis |
NP |
Nanoparticle |
ONC |
Oncogenic |
OS |
Overall survival |
OTT |
Onset To treatment |
OXPHOS |
Oxidative phosphorylation |
PAK4 |
p21-activated kinase 4 |
PBX3 |
Pre-B-cell leukemia homeobox 3 |
PD-1 |
Programmed cell death protein 1 |
PD-L1 |
Programmed death-ligand 1 |
PDK1 |
Pyruvate dehydrogenase kinase 1 |
PET |
Positron emission tomography |
PI3K |
Phosphoinositide 3-kinase |
PKM2 |
Pyruvate kinase isozyme M2 |
PPP |
Pentose–phosphate pathway |
PTEN |
Phosphatase and tensin homolog |
qRT-PCR |
Quantitative reverse transcription PCR |
RFA |
Radiofrequency ablation |
RFS |
Recurrence-free survival |
SCD1 |
Stearoyl-CoA desaturase 1 |
SMAD4 |
Small mothers against decapentaplegic 4 |
TACE |
Transarterialchemoembolisation |
TCGA |
The Cancer Genome Atlas |
TGFβR1 |
Transforming growth factor β receptor 1 |
TKIs |
Tyrosine kinase inhibitors |
TME |
Tumor microenvironment |
TNM |
Tumor–node–metastasis staging |
TS |
Tumor-suppressor |
VEGF |
Vascular endothelial growth factor |
VE-cadherin |
Vascular endothelial cadherin |
XPO1 |
Exportin 1 (gene symbol) |
YAP1 |
Yes-associated protein 1 |